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Synthetic mRNA-based gene therapy for glioblastoma: TRAIL-mRNA synergistically enhances PTEN-mRNA-based therapy

Glioblastoma (GBM) is characterized as having high molecular heterogeneity and complexity, which can be well revealed by genomic study. A truly effective treatment for GBM should flexibly address its heterogeneities, complexity, and strong drug resistance. This study was performed to explore the eff...

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Detalles Bibliográficos
Autores principales: Tang, Xiangjun, Peng, Hao, Xu, Pengfei, Zhang, Li, Fu, Rui, Tu, Hanjun, Guo, Xingrong, Huang, Kuanming, Lu, Junti, Chen, Hu, Dong, Zhiqiang, Dai, Longjun, Luo, Jie, Chen, Qianxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913249/
https://www.ncbi.nlm.nih.gov/pubmed/35317516
http://dx.doi.org/10.1016/j.omto.2022.01.013

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