SIRT6 stabilization and cytoplasmic localization in macrophages regulates acute and chronic inflammation in mice

Acute and chronic inflammations are key homeostatic events in health and disease. Sirtuins (SIRTs), a family of NAD-dependent protein deacylases, play a pivotal role in the regulation of these inflammatory responses. Indeed, SIRTs have anti-inflammatory effects through a myriad of signaling cascades...

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Detalles Bibliográficos
Autores principales: Bresque, Mariana, Cal, Karina, Pérez-Torrado, Valentina, Colman, Laura, Rodríguez-Duarte, Jorge, Vilaseca, Cecilia, Santos, Leonardo, Garat, María Pía, Ruiz, Santiago, Evans, Frances, Dapueto, Rosina, Contreras, Paola, Calliari, Aldo, Escande, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913316/
https://www.ncbi.nlm.nih.gov/pubmed/35150745
http://dx.doi.org/10.1016/j.jbc.2022.101711

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