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Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients
PURPOSE: Compared to adults, there is a paucity of data regarding the association of a positive alcohol screen (PAS) and outcomes in adolescent patients with traumatic brain injury (TBI). We hypothesize adolescent TBI patients with a PAS on admission to have increased mortality compared to patients...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913449/ https://www.ncbi.nlm.nih.gov/pubmed/34958420 http://dx.doi.org/10.1007/s00383-021-05057-z |
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author | Lu, Zachary N. Yeates, Eric O. Grigorian, Areg Algeo, Russell G. Kuza, Catherine M. Chin, Theresa L. Donnelly, Megan Kong, Allen Nahmias, Jeffry |
author_facet | Lu, Zachary N. Yeates, Eric O. Grigorian, Areg Algeo, Russell G. Kuza, Catherine M. Chin, Theresa L. Donnelly, Megan Kong, Allen Nahmias, Jeffry |
author_sort | Lu, Zachary N. |
collection | PubMed |
description | PURPOSE: Compared to adults, there is a paucity of data regarding the association of a positive alcohol screen (PAS) and outcomes in adolescent patients with traumatic brain injury (TBI). We hypothesize adolescent TBI patients with a PAS on admission to have increased mortality compared to patients with a negative alcohol screen. METHODS: The 2017 Trauma Quality Improvement Program database was queried for patients aged 13–17 years presenting with a TBI and serum alcohol screen. Patients with missing information regarding midline shift on imaging and Glasgow Coma Scale (GCS) score were excluded. A multivariable logistic regression analysis for mortality was performed. RESULTS: From 2553 adolescent TBI patients with an alcohol screen, 220 (8.6%) had a PAS. Median injury severity scores and rates of penetrating trauma (all p > 0.05) were similar between alcohol positive and negative patients. Patients with a PAS had a similar mortality rate (13.2% vs. 12.1%, p = 0.64) compared to patients with a negative screen. Multivariate logistic regression controlling for risk factors associated with mortality revealed a PAS to confer a similar risk of mortality compared to alcohol negative patients (p = 0.40). CONCLUSION: Adolescent TBI patients with a PAS had similar associated risk of mortality compared to patients with a negative alcohol screen. |
format | Online Article Text |
id | pubmed-8913449 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-89134492022-03-15 Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients Lu, Zachary N. Yeates, Eric O. Grigorian, Areg Algeo, Russell G. Kuza, Catherine M. Chin, Theresa L. Donnelly, Megan Kong, Allen Nahmias, Jeffry Pediatr Surg Int Original Article PURPOSE: Compared to adults, there is a paucity of data regarding the association of a positive alcohol screen (PAS) and outcomes in adolescent patients with traumatic brain injury (TBI). We hypothesize adolescent TBI patients with a PAS on admission to have increased mortality compared to patients with a negative alcohol screen. METHODS: The 2017 Trauma Quality Improvement Program database was queried for patients aged 13–17 years presenting with a TBI and serum alcohol screen. Patients with missing information regarding midline shift on imaging and Glasgow Coma Scale (GCS) score were excluded. A multivariable logistic regression analysis for mortality was performed. RESULTS: From 2553 adolescent TBI patients with an alcohol screen, 220 (8.6%) had a PAS. Median injury severity scores and rates of penetrating trauma (all p > 0.05) were similar between alcohol positive and negative patients. Patients with a PAS had a similar mortality rate (13.2% vs. 12.1%, p = 0.64) compared to patients with a negative screen. Multivariate logistic regression controlling for risk factors associated with mortality revealed a PAS to confer a similar risk of mortality compared to alcohol negative patients (p = 0.40). CONCLUSION: Adolescent TBI patients with a PAS had similar associated risk of mortality compared to patients with a negative alcohol screen. Springer Berlin Heidelberg 2021-12-27 2022 /pmc/articles/PMC8913449/ /pubmed/34958420 http://dx.doi.org/10.1007/s00383-021-05057-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Lu, Zachary N. Yeates, Eric O. Grigorian, Areg Algeo, Russell G. Kuza, Catherine M. Chin, Theresa L. Donnelly, Megan Kong, Allen Nahmias, Jeffry Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients |
title | Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients |
title_full | Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients |
title_fullStr | Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients |
title_full_unstemmed | Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients |
title_short | Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients |
title_sort | alcohol is not associated with increased mortality in adolescent traumatic brain injury patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913449/ https://www.ncbi.nlm.nih.gov/pubmed/34958420 http://dx.doi.org/10.1007/s00383-021-05057-z |
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