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Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients

PURPOSE: Compared to adults, there is a paucity of data regarding the association of a positive alcohol screen (PAS) and outcomes in adolescent patients with traumatic brain injury (TBI). We hypothesize adolescent TBI patients with a PAS on admission to have increased mortality compared to patients...

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Autores principales: Lu, Zachary N., Yeates, Eric O., Grigorian, Areg, Algeo, Russell G., Kuza, Catherine M., Chin, Theresa L., Donnelly, Megan, Kong, Allen, Nahmias, Jeffry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913449/
https://www.ncbi.nlm.nih.gov/pubmed/34958420
http://dx.doi.org/10.1007/s00383-021-05057-z
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author Lu, Zachary N.
Yeates, Eric O.
Grigorian, Areg
Algeo, Russell G.
Kuza, Catherine M.
Chin, Theresa L.
Donnelly, Megan
Kong, Allen
Nahmias, Jeffry
author_facet Lu, Zachary N.
Yeates, Eric O.
Grigorian, Areg
Algeo, Russell G.
Kuza, Catherine M.
Chin, Theresa L.
Donnelly, Megan
Kong, Allen
Nahmias, Jeffry
author_sort Lu, Zachary N.
collection PubMed
description PURPOSE: Compared to adults, there is a paucity of data regarding the association of a positive alcohol screen (PAS) and outcomes in adolescent patients with traumatic brain injury (TBI). We hypothesize adolescent TBI patients with a PAS on admission to have increased mortality compared to patients with a negative alcohol screen. METHODS: The 2017 Trauma Quality Improvement Program database was queried for patients aged 13–17 years presenting with a TBI and serum alcohol screen. Patients with missing information regarding midline shift on imaging and Glasgow Coma Scale (GCS) score were excluded. A multivariable logistic regression analysis for mortality was performed. RESULTS: From 2553 adolescent TBI patients with an alcohol screen, 220 (8.6%) had a PAS. Median injury severity scores and rates of penetrating trauma (all p > 0.05) were similar between alcohol positive and negative patients. Patients with a PAS had a similar mortality rate (13.2% vs. 12.1%, p = 0.64) compared to patients with a negative screen. Multivariate logistic regression controlling for risk factors associated with mortality revealed a PAS to confer a similar risk of mortality compared to alcohol negative patients (p = 0.40). CONCLUSION: Adolescent TBI patients with a PAS had similar associated risk of mortality compared to patients with a negative alcohol screen.
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spelling pubmed-89134492022-03-15 Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients Lu, Zachary N. Yeates, Eric O. Grigorian, Areg Algeo, Russell G. Kuza, Catherine M. Chin, Theresa L. Donnelly, Megan Kong, Allen Nahmias, Jeffry Pediatr Surg Int Original Article PURPOSE: Compared to adults, there is a paucity of data regarding the association of a positive alcohol screen (PAS) and outcomes in adolescent patients with traumatic brain injury (TBI). We hypothesize adolescent TBI patients with a PAS on admission to have increased mortality compared to patients with a negative alcohol screen. METHODS: The 2017 Trauma Quality Improvement Program database was queried for patients aged 13–17 years presenting with a TBI and serum alcohol screen. Patients with missing information regarding midline shift on imaging and Glasgow Coma Scale (GCS) score were excluded. A multivariable logistic regression analysis for mortality was performed. RESULTS: From 2553 adolescent TBI patients with an alcohol screen, 220 (8.6%) had a PAS. Median injury severity scores and rates of penetrating trauma (all p > 0.05) were similar between alcohol positive and negative patients. Patients with a PAS had a similar mortality rate (13.2% vs. 12.1%, p = 0.64) compared to patients with a negative screen. Multivariate logistic regression controlling for risk factors associated with mortality revealed a PAS to confer a similar risk of mortality compared to alcohol negative patients (p = 0.40). CONCLUSION: Adolescent TBI patients with a PAS had similar associated risk of mortality compared to patients with a negative alcohol screen. Springer Berlin Heidelberg 2021-12-27 2022 /pmc/articles/PMC8913449/ /pubmed/34958420 http://dx.doi.org/10.1007/s00383-021-05057-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Lu, Zachary N.
Yeates, Eric O.
Grigorian, Areg
Algeo, Russell G.
Kuza, Catherine M.
Chin, Theresa L.
Donnelly, Megan
Kong, Allen
Nahmias, Jeffry
Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients
title Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients
title_full Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients
title_fullStr Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients
title_full_unstemmed Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients
title_short Alcohol is not associated with increased mortality in adolescent traumatic brain injury patients
title_sort alcohol is not associated with increased mortality in adolescent traumatic brain injury patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913449/
https://www.ncbi.nlm.nih.gov/pubmed/34958420
http://dx.doi.org/10.1007/s00383-021-05057-z
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