Cargando…
iRhom pseudoproteases regulate ER stress-induced cell death through IP(3) receptors and BCL-2
The folding capacity of membrane and secretory proteins in the endoplasmic reticulum (ER) can be challenged by physiological and pathological perturbations, causing ER stress. If unresolved, this leads to cell death. We report a role for iRhom pseudoproteases in controlling apoptosis due to persiste...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913617/ https://www.ncbi.nlm.nih.gov/pubmed/35273168 http://dx.doi.org/10.1038/s41467-022-28930-4 |