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Downregulation of TPX2 impairs the antitumor activity of CD8+ T cells in hepatocellular carcinoma

Targeting key genes that play dominant roles in T cell dysfunction is an efficient strategy for cancer immunotherapy. Here, we aimed to investigate the role of TPX2 in the antitumor effect of CD8 + T cells in hepatocellular carcinoma (HCC). Flow cytometry was used to assay the level of cell surface...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaochen, Wang, Jianchu, Shen, Haiyuan, Luo, Zongjiang, Lu, Xiaojie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913637/ https://www.ncbi.nlm.nih.gov/pubmed/35273149 http://dx.doi.org/10.1038/s41419-022-04645-8

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