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High drug-loaded microspheres enabled by controlled in-droplet precipitation promote functional recovery after spinal cord injury
Drug delivery systems with high content of drug can minimize excipients administration, reduce side effects, improve therapeutic efficacy and/or promote patient compliance. However, engineering such systems is extremely challenging, as their loading capacity is inherently limited by the compatibilit...
Autores principales: | Li, Wei, Chen, Jian, Zhao, Shujie, Huang, Tianhe, Ying, Huiyan, Trujillo, Claudia, Molinaro, Giuseppina, Zhou, Zheng, Jiang, Tao, Liu, Wei, Li, Linwei, Bai, Yuancheng, Quan, Peng, Ding, Yaping, Hirvonen, Jouni, Yin, Guoyong, Santos, Hélder A., Fan, Jin, Liu, Dongfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913677/ https://www.ncbi.nlm.nih.gov/pubmed/35273148 http://dx.doi.org/10.1038/s41467-022-28787-7 |
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