Elevated Kir2.1/nuclear N2ICD defines a highly malignant subtype of non-WNT/SHH medulloblastomas

Medulloblastoma (MB) is one of the most common childhood malignant brain tumors (WHO grade IV), traditionally divided into WNT, SHH, Group 3, and Group 4 subgroups based on the transcription profiles, somatic DNA alterations, and clinical outcomes. Unlike WNT and SHH subgroup MBs, Group 3 and Group...

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Detalles Bibliográficos
Autores principales: Wang, Yan-Xia, Wu, Haibo, Ren, Yong, Lv, Shengqing, Ji, Chengdong, Xiang, Dongfang, Zhang, Mengsi, Lu, Huimin, Fu, Wenjuan, Liu, Qing, Yan, Zexuan, Ma, Qinghua, Miao, Jingya, Cai, Ruili, Lan, Xi, Wu, Bin, Wang, Wenying, Liu, Yinhua, Wang, Dai-Zhong, Cao, Mianfu, He, Zhicheng, Shi, Yu, Ping, Yifang, Yao, Xiaohong, Zhang, Xia, Zhang, Peng, Wang, Ji Ming, Wang, Yan, Cui, Youhong, Bian, Xiu-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913686/
https://www.ncbi.nlm.nih.gov/pubmed/35273141
http://dx.doi.org/10.1038/s41392-022-00890-7

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