Novel indolic AMPK modulators induce vasodilatation through activation of the AMPK–eNOS–NO pathway

Endothelial adenosine monophosphate-activated protein kinase (AMPK) plays a critical role in the regulation of vascular tone through stimulating nitric oxide (NO) release in endothelial cells. Since obesity leads to endothelial dysfunction and AMPK dysregulation, AMPK activation might be an importan...

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Detalles Bibliográficos
Autores principales: Sanz-Gómez, Marta, Aledavood, Elnaz, Beroiz-Salaverri, Marina, Lagartera, Laura, Vega-Martín, Elena, Gil-Ortega, Marta, Cumella, Jose, Pérez, Concepción, Luque, Francisco Javier, Estarellas, Carolina, Fernández-Alfonso, María S., Castro, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913687/
https://www.ncbi.nlm.nih.gov/pubmed/35273216
http://dx.doi.org/10.1038/s41598-022-07077-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913687/
https://www.ncbi.nlm.nih.gov/pubmed/35273216
http://dx.doi.org/10.1038/s41598-022-07077-8

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