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Integrated metagenomics identifies a crucial role for trimethylamine-producing Lachnoclostridium in promoting atherosclerosis

Microbial trimethylamine (TMA)-lyase activity promotes the development of atherosclerosis by generating of TMA, the precursor of TMA N-oxide (TMAO). TMAO is well documented, but same can not be said of TMA-producing bacteria. This work aimed to identify TMA-producing genera in human intestinal micro...

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Detalles Bibliográficos
Autores principales: Cai, Yuan-Yuan, Huang, Feng-Qing, Lao, Xingzhen, Lu, Yawen, Gao, Xuejiao, Alolga, Raphael N., Yin, Kunpeng, Zhou, Xingchen, Wang, Yun, Liu, Baolin, Shang, Jing, Qi, Lian-Wen, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913745/
https://www.ncbi.nlm.nih.gov/pubmed/35273169
http://dx.doi.org/10.1038/s41522-022-00273-4

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