Cargando…

A Thermostable Oral SARS-CoV-2 Vaccine Induces Mucosal and Protective Immunity

An ideal protective vaccine against SARS-CoV-2 should not only be effective in preventing disease, but also in preventing virus transmission. It should also be well accepted by the population and have a simple logistic chain. To fulfill these criteria, we developed a thermostable, orally administere...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bellier, Bertrand, Saura, Alicia, Luján, Lucas A., Molina, Cecilia R., Luján, Hugo D., Klatzmann, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8913903/ https://www.ncbi.nlm.nih.gov/pubmed/35281065 http://dx.doi.org/10.3389/fimmu.2022.837443

Ejemplares similares

Intranasal Delivery of Thermostable Subunit Vaccine for Cross-Reactive Mucosal and Systemic Antibody Responses Against SARS-CoV-2
por: Nguyen, Khue G., et al.
Publicado: (2022)

Efficient oral vaccination by bioengineering virus-like particles with protozoan surface proteins
por: Serradell, Marianela C., et al.
Publicado: (2019)

Human and Mouse CD8(+)CD25(+)FOXP3(+) Regulatory T Cells at Steady State and during Interleukin-2 Therapy
por: Churlaud, Guillaume, et al.
Publicado: (2015)

Systems biology in vaccine design
por: Six, Adrien, et al.
Publicado: (2012)

Editorial: Mucosal immunity to HIV and SARS-CoV-2 infection and vaccination
por: Bomsel, Morgane, et al.
Publicado: (2023)

Protection from COVID-19 disease in hamsters vaccinated with subunit SARS-CoV-2 S1 mucosal vaccines adjuvanted with different adjuvants
por: Sui, Yongjun, et al.
Publicado: (2023)

A nasal vaccine with inactivated whole-virion elicits protective mucosal immunity against SARS-CoV-2 in mice
por: Tokunoh, Nagisa, et al.
Publicado: (2023)

The Mucosal and Serological Immune Responses to the Novel Coronavirus (SARS-CoV-2) Vaccines
por: Chan, Renee W. Y., et al.
Publicado: (2021)

The Bacterial Mucosal Immunotherapy MV130 Protects Against SARS-CoV-2 Infection and Improves COVID-19 Vaccines Immunogenicity
por: del Fresno, Carlos, et al.
Publicado: (2021)

An Intranasal OMV-Based Vaccine Induces High Mucosal and Systemic Protecting Immunity Against a SARS-CoV-2 Infection
por: van der Ley, Peter A., et al.
Publicado: (2021)

Mucosal immunization with Ad5-based vaccines protects Syrian hamsters from challenge with omicron and delta variants of SARS-CoV-2
por: Braun, Molly R., et al.
Publicado: (2023)

Vaccination of domestic animals with a novel oral vaccine prevents Giardia infections, alleviates signs of giardiasis and reduces transmission to humans
por: Serradell, Marianela C, et al.
Publicado: (2016)

An Overview of Challenges Limiting the Design of Protective Mucosal Vaccines for Finfish
por: Munang’andu, Hetron Mweemba, et al.
Publicado: (2015)

A Simplified SARS-CoV-2 Mouse Model Demonstrates Protection by an Oral Replicon-Based mRNA Vaccine
por: Jawalagatti, Vijayakumar, et al.
Publicado: (2022)

Oral inactivated whole cell vaccine for mucosal immunization: ETVAX case study
por: Walker, Richard I., et al.
Publicado: (2023)

Oral Mucosal Epithelial Cells
por: Groeger, Sabine, et al.
Publicado: (2019)

Dual-Antigen COVID-19 Vaccine Subcutaneous Prime Delivery With Oral Boosts Protects NHP Against SARS-CoV-2 Challenge
por: Gabitzsch, Elizabeth, et al.
Publicado: (2021)

Gut mucosal immune responses and protective efficacy of oral yeast Cyprinid herpesvirus 2 (CyHV-2) vaccine in Carassius auratus gibelio
por: Dong, Zhao-Ran, et al.
Publicado: (2022)

mRNA vaccination drives differential mucosal neutralizing antibody profiles in naïve and SARS-CoV-2 previously-infected individuals
por: Longet, Stephanie, et al.
Publicado: (2022)

Editorial: Mucosal Vaccination: Strategies to Induce and Evaluate Mucosal Immunity
por: Kozlowski, Pamela A., et al.
Publicado: (2022)

Mucosal immunity: The missing link in comprehending SARS-CoV-2 infection and transmission
por: Russell, Michael W., et al.
Publicado: (2022)

Could BCG Vaccination Induce Protective Trained Immunity for SARS-CoV-2?
por: Covián, Camila, et al.
Publicado: (2020)

Combination of a Sindbis-SARS-CoV-2 Spike Vaccine and αOX40 Antibody Elicits Protective Immunity Against SARS-CoV-2 Induced Disease and Potentiates Long-Term SARS-CoV-2-Specific Humoral and T-Cell Immunity
por: Scaglione, Antonella, et al.
Publicado: (2021)

Effectiveness and waning of protection with the BNT162b2 vaccine against the SARS-CoV-2 Delta variant in immunocompromised individuals
por: Szekanecz, Zoltán, et al.
Publicado: (2023)

Infection and Immune Memory: Variables in Robust Protection by Vaccines Against SARS-CoV-2
por: Ahluwalia, Pankaj, et al.
Publicado: (2021)

Pivotal role of tissue-resident memory lymphocytes in the control of mucosal infections: can mucosal vaccination induce protective tissue-resident memory T and B cells?
por: Longet, Stephanie, et al.
Publicado: (2023)

Editorial: Oral mucosal immunity: homeostasis and inflammation
por: Zhang, Dunfang, et al.
Publicado: (2023)

Systemic and Mucosal B and T Cell Responses Upon Mucosal Vaccination of Teleost Fish
por: Muñoz-Atienza, Estefanía, et al.
Publicado: (2021)

The role of vaccination route with an adenovirus-vectored vaccine in protection, viral control, and transmission in the SARS-CoV-2/K18-hACE2 mouse infection model
por: Dickson, Alexandria, et al.
Publicado: (2023)

Mucosal Immunity in COVID-19: A Neglected but Critical Aspect of SARS-CoV-2 Infection
por: Russell, Michael W., et al.
Publicado: (2020)

SARS-CoV-2 bivalent mRNA vaccine with broad protection against variants of concern
por: Ma, Qinhai, et al.
Publicado: (2023)

Enhanced protective efficacy of a thermostable RBD-S2 vaccine formulation against SARS-CoV-2 and its variants
por: Mittal, Nidhi, et al.
Publicado: (2023)

Mucosal Immunity and Protective Efficacy of Intranasal Inactivated Influenza Vaccine Is Improved by Chitosan Nanoparticle Delivery in Pigs
por: Dhakal, Santosh, et al.
Publicado: (2018)

Mucosal immunization with an adenoviral vector vaccine confers superior protection against RSV compared to natural immunity
por: Maier, Clara, et al.
Publicado: (2022)

Superior humoral immunity in vaccinated SARS-CoV-2 convalescence as compared to SARS-COV-2 infection or vaccination
por: Paniskaki, Krystallenia, et al.
Publicado: (2022)

SARS-CoV-2 Specific IgG Antibodies Persist Over a 12-Month Period in Oral Mucosal Fluid Collected From Previously Infected Individuals
por: Chellamuthu, Prithivi, et al.
Publicado: (2021)

Distinct Features and Functions of Systemic and Mucosal Humoral Immunity Among SARS-CoV-2 Convalescent Individuals
por: Butler, Savannah E., et al.
Publicado: (2021)

Differences in systemic and mucosal SARS-CoV-2 antibody prevalence in a prospective cohort of Dutch children
por: Keuning, Maya W., et al.
Publicado: (2022)

Protective antigenic epitopes revealed by immunosignatures after three doses of inactivated SARS-CoV-2 vaccine
por: Peng, Mian, et al.
Publicado: (2022)

Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi
por: Sanchez Alberti, Andrés, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_al4cjid43b7r11sn10md3uchvj