Human N-Acetyltransferase 1 and 2 Differ in Affinity Towards Acetyl-Coenzyme A Cofactor and N-Hydroxy-Arylamine Carcinogens

Arylamine N-acetyltransferases catalyze the transfer of acetyl groups from the endogenous cofactor acetyl coenzyme A (AcCoA) to arylamine (N-acetylation) and N-hydroxy-arylamine (O-acetylation) acceptors. Humans express two arylamine N-acetyltransferase isozymes (NAT1 and NAT2) which catalyze both N...

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Detalles Bibliográficos
Autores principales: Hein, David W., Doll, Mark A., Habil, Mariam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914035/
https://www.ncbi.nlm.nih.gov/pubmed/35281898
http://dx.doi.org/10.3389/fphar.2022.821133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914035/
https://www.ncbi.nlm.nih.gov/pubmed/35281898
http://dx.doi.org/10.3389/fphar.2022.821133

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