Cargando…

New Insights of CCR7 Signaling in Dendritic Cell Migration and Inflammatory Diseases

CCR7, collaborated with its ligands CCL19 and CCL21, controls extensive migratory events in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph nodes, initiating the antigen presentation and T-cell response. Abnormal expression of CCR7 in dendritic cells will cause a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hong, Wenxiang, Yang, Bo, He, Qiaojun, Wang, Jiajia, Weng, Qinjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914285/ https://www.ncbi.nlm.nih.gov/pubmed/35281921 http://dx.doi.org/10.3389/fphar.2022.841687

Ejemplares similares

Targeting Microglia and Macrophages: A Potential Treatment Strategy for Multiple Sclerosis
por: Wang, Jiaying, et al.
Publicado: (2019)

Challenges and Improvements of Novel Therapies for Ischemic Stroke
por: Yang, Lijun, et al.
Publicado: (2021)

Role of DJ-1 in Immune and Inflammatory Diseases
por: Zhang, Lulu, et al.
Publicado: (2020)

Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling
por: Wang, Jiajia, et al.
Publicado: (2021)

Targeting PI3K/AKT signaling for treatment of idiopathic pulmonary fibrosis
por: Wang, Jincheng, et al.
Publicado: (2022)

Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration
por: Guak, Hannah, et al.
Publicado: (2018)

Jak3 Is Involved in Dendritic Cell Maturation and CCR7-Dependent Migration
por: Rivas-Caicedo, Ana, et al.
Publicado: (2009)

Immune complexes stimulate CCR7-dependent dendritic cell migration to lymph nodes
por: Clatworthy, Menna R., et al.
Publicado: (2014)

Dendritic cells derived exosomes migration to spleen and induction of inflammation are regulated by CCR7
por: Wei, Gao, et al.
Publicado: (2017)

CCR7 deficient inflammatory Dendritic Cells are retained in the Central Nervous System
por: Clarkson, Benjamin D., et al.
Publicado: (2017)

HHV-8 reduces dendritic cell migration through down-regulation of cell-surface CCR6 and CCR7 and cytoskeleton reorganization
por: Cirone, Mara, et al.
Publicado: (2012)

Regulation of CCR7-dependent cell migration through CCR7 homodimer formation
por: Kobayashi, Daichi, et al.
Publicado: (2017)

A Set of Experimentally Validated Decoys for the Human CC Chemokine Receptor 7 (CCR7) Obtained by Virtual Screening
por: Proj, Matic, et al.
Publicado: (2022)

CCR7 Signals Are Essential for Cortex–Medulla Migration of Developing Thymocytes
por: Ueno, Tomoo, et al.
Publicado: (2004)

Adenovirus-Mediated CCR7 and BTLA Overexpression Enhances Immune Tolerance and Migration in Immature Dendritic Cells
por: Xin, Haiming, et al.
Publicado: (2017)

CAL-1 as Cellular Model System to Study CCR7-Guided Human Dendritic Cell Migration
por: Uetz-von Allmen, Edith, et al.
Publicado: (2021)

Distinct Fates of Chemokine and Surrogate Molecule Gradients: Consequences for CCR7-Guided Dendritic Cell Migration
por: Artinger, Marc, et al.
Publicado: (2022)

Targeting Ubiquitin-Specific Protease 7 (USP7) in Cancer: A New Insight to Overcome Drug Resistance
por: Lu, Jiabin, et al.
Publicado: (2021)

CCR7 Mediates Dendritic-Cell-Derived Exosome Migration and Improves Cardiac Function after Myocardial Infarction
por: Zhang, Youming, et al.
Publicado: (2023)

New Insights Into the Epigenetic Regulation of Inflammatory Bowel Disease
por: Xu, Jing, et al.
Publicado: (2022)

FSH promotes immature porcine Sertoli cell proliferation by activating the CCR7/Ras-ERK signaling axis
por: Yin, Yanfei, et al.
Publicado: (2023)

Genetic dominance of transforming growth factor-β1 polymorphisms in chronic liver disease
por: Cai, Xuanyan, et al.
Publicado: (2022)

CCR9 overexpression promotes T-ALL progression by enhancing cholesterol biosynthesis
por: Jamal, Muhammad, et al.
Publicado: (2023)

MicroRNA-532-3p Suppresses Malignant Behaviors of Tongue Squamous Cell Carcinoma via Regulating CCR7
por: Feng, Cuijuan, et al.
Publicado: (2019)

CRISPR/Cas9 Immunoengineering of Hoxb8-Immortalized Progenitor Cells for Revealing CCR7-Mediated Dendritic Cell Signaling and Migration Mechanisms in vivo
por: Hammerschmidt, Swantje I., et al.
Publicado: (2018)

Systematic Assessment of Chemokine Signaling at Chemokine Receptors CCR4, CCR7 and CCR10
por: Lim, Herman D., et al.
Publicado: (2021)

New Insights Into Peptide Cannabinoids: Structure, Biosynthesis and Signaling
por: Riquelme-Sandoval, Agustín, et al.
Publicado: (2020)

The Chemokine Receptor CCR7 Uses Distinct Signaling Modules With Biased Functionality to Regulate Dendritic Cells
por: Rodríguez-Fernández, José Luis, et al.
Publicado: (2020)

Inhibition of Ubiquitin-Specific Proteases as a Novel Anticancer Therapeutic Strategy
por: Yuan, Tao, et al.
Publicado: (2018)

Gamma-ray Irradiation Impairs Dendritic Cell Migration to CCL19 by Down-regulation of CCR7 and Induction of Cell Apoptosis
por: Liu, Cong, et al.
Publicado: (2011)

Simultaneous Quantification and Pharmacokinetic Study of Five Homologs of Dalbavancin in Rat Plasma Using UHPLC-MS/MS
por: Zhu, Difeng, et al.
Publicado: (2020)

Synergistic antitumor activity of regorafenib and rosuvastatin in colorectal cancer
por: Yuan, Tao, et al.
Publicado: (2023)

Targeting Myc Interacting Proteins as a Winding Path in Cancer Therapy
por: Zhou, Yihui, et al.
Publicado: (2021)

Corrigendum: Targeting Myc Interacting Proteins as a Winding Path in Cancer Therapy
por: Zhou, Yihui, et al.
Publicado: (2021)

Bafetinib Suppresses the Transcription of PD-L1 Through c-Myc in Lung Cancer
por: Chen, Xi, et al.
Publicado: (2022)

Low CCR7-Mediated Migration of Human Monocyte Derived Dendritic Cells in Response to Human Respiratory Syncytial Virus and Human Metapneumovirus
por: Le Nouën, Cyril, et al.
Publicado: (2011)

Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity
por: Weng, Qinjie, et al.
Publicado: (2017)

ORM Promotes Skeletal Muscle Glycogen Accumulation via CCR5-Activated AMPK Pathway in Mice
por: Qin, Zhen, et al.
Publicado: (2016)

New Insights in Cardiac β-Adrenergic Signaling During Heart Failure and Aging
por: de Lucia, Claudio, et al.
Publicado: (2018)

Targeting Nrf2-Mediated Oxidative Stress Response Signaling Pathways as New Therapeutic Strategy for Pituitary Adenomas
por: Zhan, Xianquan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_f67uarsjo1oga31qvr836j9efr