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Vincristine dosing, drug exposure and therapeutic drug monitoring in neonate and infant cancer patients

BACKGROUND: The anticancer drug vincristine is associated with potentially dose-limiting side-effects, including neurotoxicity and myelosuppression. However, there currently exists a lack of published clinical pharmacology data relating to its use in neonate and infant patients. We report a study in...

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Detalles Bibliográficos
Autores principales: Barnett, Shelby, Hellmann, Farina, Parke, Elizabeth, Makin, Guy, Tweddle, Deborah A., Osborne, Caroline, Hempel, Georg, Veal, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914346/
https://www.ncbi.nlm.nih.gov/pubmed/34657763
http://dx.doi.org/10.1016/j.ejca.2021.09.014

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