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Interaction of transcription factor FoxO3 with histone acetyltransferase complex subunit TRRAP modulates gene expression and apoptosis

Forkhead box O (FoxO) transcription factors are conserved proteins involved in the regulation of life span and age-related diseases, such as diabetes and cancer. Stress stimuli or growth factor deprivation promotes nuclear localization and activation of FoxO proteins, which—depending on the cellular...

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Detalles Bibliográficos
Autores principales: Fusi, Lorenza, Paudel, Rupesh, Meder, Katharina, Schlosser, Andreas, Schrama, David, Goebeler, Matthias, Schmidt, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914384/
https://www.ncbi.nlm.nih.gov/pubmed/35151693
http://dx.doi.org/10.1016/j.jbc.2022.101714