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Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus

Enzymes in the thiol redox systems of microbial pathogens are promising targets for drug development. In this study we characterized the thioredoxin reductase (TrxR) selenoproteins from Brugia malayi and Onchocerca volvulus, filarial nematode parasites and causative agents of lymphatic filariasis an...

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Detalles Bibliográficos
Autores principales:	Fata, Francesca, Gencheva, Radosveta, Cheng, Qing, Lullo, Rachel, Ardini, Matteo, Silvestri, Ilaria, Gabriele, Federica, Ippoliti, Rodolfo, Bulman, Christina A., Sakanari, Judy A., Williams, David L., Arnér, Elias S.J., Angelucci, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914392/ https://www.ncbi.nlm.nih.gov/pubmed/35276442 http://dx.doi.org/10.1016/j.redox.2022.102278

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