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The Unfolded Protein Responses in Health, Aging, and Neurodegeneration: Recent Advances and Future Considerations

Aging and age-related neurodegeneration are both associated with the accumulation of unfolded and abnormally folded proteins, highlighting the importance of protein homeostasis (termed proteostasis) in maintaining organismal health. To this end, two cellular compartments with essential protein foldi...

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Detalles Bibliográficos
Autores principales: Wodrich, Andrew P. K., Scott, Andrew W., Shukla, Arvind Kumar, Harris, Brent T., Giniger, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914544/
https://www.ncbi.nlm.nih.gov/pubmed/35283733
http://dx.doi.org/10.3389/fnmol.2022.831116