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The Unfolded Protein Responses in Health, Aging, and Neurodegeneration: Recent Advances and Future Considerations
Aging and age-related neurodegeneration are both associated with the accumulation of unfolded and abnormally folded proteins, highlighting the importance of protein homeostasis (termed proteostasis) in maintaining organismal health. To this end, two cellular compartments with essential protein foldi...
Autores principales: | Wodrich, Andrew P. K., Scott, Andrew W., Shukla, Arvind Kumar, Harris, Brent T., Giniger, Edward |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914544/ https://www.ncbi.nlm.nih.gov/pubmed/35283733 http://dx.doi.org/10.3389/fnmol.2022.831116 |
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