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TET2 Regulates 5-Hydroxymethylcytosine Signature and CD4(+) T-Cell Balance in Allergic Rhinitis

PURPOSE: Previous studies have shown the role of ten-eleven translocation 2 (TET2) in CD4(+) T cells. However, its function in CD4(+) T cells under allergic inflammation is unclear. We aimed to investigate the epigenomic distribution of DNA 5-hydroxymethylcytosine (5hmC) and the role of TET2 in CD4(...

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Detalles Bibliográficos
Autores principales: Tan, Lu, Fu, Lisheng, Zheng, Li, Fan, Wenjun, Tan, Hanyu, Tao, Zezhang, Xu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8914607/
https://www.ncbi.nlm.nih.gov/pubmed/35255541
http://dx.doi.org/10.4168/aair.2022.14.2.254