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Epidemiological analysis of rubella-confirmed cases from measles-suspected cases in Ethiopia: threat for congenital rubella syndrome

Rubella is a highly contagious mild viral illness. It is a leading cause of congenital rubella syndrome (CRS). Routine data of rubella do not exist in Ethiopia. However, laboratory-based conformation of rubella cases from measles negative samples were collected from a measles surveillance system. Th...

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Autores principales: Gemechu, Diriba Sufa, Worku, Yoseph, Edae, Zewdu Assefa, Feyisa, Yohannis Dugasa, Watere, Shambel Habebe, Woyessa, Abyot Bekele, Dukessa, Abebe, Gerema, Urge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915192/
https://www.ncbi.nlm.nih.gov/pubmed/35225215
http://dx.doi.org/10.1017/S0950268822000279
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author Gemechu, Diriba Sufa
Worku, Yoseph
Edae, Zewdu Assefa
Feyisa, Yohannis Dugasa
Watere, Shambel Habebe
Woyessa, Abyot Bekele
Dukessa, Abebe
Gerema, Urge
author_facet Gemechu, Diriba Sufa
Worku, Yoseph
Edae, Zewdu Assefa
Feyisa, Yohannis Dugasa
Watere, Shambel Habebe
Woyessa, Abyot Bekele
Dukessa, Abebe
Gerema, Urge
author_sort Gemechu, Diriba Sufa
collection PubMed
description Rubella is a highly contagious mild viral illness. It is a leading cause of congenital rubella syndrome (CRS). Routine data of rubella do not exist in Ethiopia. However, laboratory-based conformation of rubella cases from measles negative samples were collected from a measles surveillance system. The current study was to analyse the epidemiological distribution of rubella cases from measles-suspected cases in Ethiopia from 2011 to 2015. National-based secondary data analysis of rubella through measles-based surveillances was carried out. Measles-suspected cases were investigated using the case investigation form, and a serum sample collected and sent to the Ethiopian laboratory for conformation. Samples tested for measles immunoglobulin M (IgM) were tested for rubella. The investigation results were entered into an electronic database using SPSS version 25 for analysis. Out of 11749 samples tested for rubella IgM from 2011 to 2015, 2295 (19.5%) were positive for rubella IgM and 51% of rubella-positive cases were female. Five per cent of all cases were female aged between 15 and 49. Cases were confirmed from all regions, two administrative towns and seasonal variations were observed with peaks in the first and fourth seasonal periods of the years. As fear of congenital abnormality (CRS), the Ethiopian government should focus on rubella syndrome surveillance with the aim of starting a rubella vaccine.
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spelling pubmed-89151922022-03-21 Epidemiological analysis of rubella-confirmed cases from measles-suspected cases in Ethiopia: threat for congenital rubella syndrome Gemechu, Diriba Sufa Worku, Yoseph Edae, Zewdu Assefa Feyisa, Yohannis Dugasa Watere, Shambel Habebe Woyessa, Abyot Bekele Dukessa, Abebe Gerema, Urge Epidemiol Infect Original Paper Rubella is a highly contagious mild viral illness. It is a leading cause of congenital rubella syndrome (CRS). Routine data of rubella do not exist in Ethiopia. However, laboratory-based conformation of rubella cases from measles negative samples were collected from a measles surveillance system. The current study was to analyse the epidemiological distribution of rubella cases from measles-suspected cases in Ethiopia from 2011 to 2015. National-based secondary data analysis of rubella through measles-based surveillances was carried out. Measles-suspected cases were investigated using the case investigation form, and a serum sample collected and sent to the Ethiopian laboratory for conformation. Samples tested for measles immunoglobulin M (IgM) were tested for rubella. The investigation results were entered into an electronic database using SPSS version 25 for analysis. Out of 11749 samples tested for rubella IgM from 2011 to 2015, 2295 (19.5%) were positive for rubella IgM and 51% of rubella-positive cases were female. Five per cent of all cases were female aged between 15 and 49. Cases were confirmed from all regions, two administrative towns and seasonal variations were observed with peaks in the first and fourth seasonal periods of the years. As fear of congenital abnormality (CRS), the Ethiopian government should focus on rubella syndrome surveillance with the aim of starting a rubella vaccine. Cambridge University Press 2022-02-28 /pmc/articles/PMC8915192/ /pubmed/35225215 http://dx.doi.org/10.1017/S0950268822000279 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
spellingShingle Original Paper
Gemechu, Diriba Sufa
Worku, Yoseph
Edae, Zewdu Assefa
Feyisa, Yohannis Dugasa
Watere, Shambel Habebe
Woyessa, Abyot Bekele
Dukessa, Abebe
Gerema, Urge
Epidemiological analysis of rubella-confirmed cases from measles-suspected cases in Ethiopia: threat for congenital rubella syndrome
title Epidemiological analysis of rubella-confirmed cases from measles-suspected cases in Ethiopia: threat for congenital rubella syndrome
title_full Epidemiological analysis of rubella-confirmed cases from measles-suspected cases in Ethiopia: threat for congenital rubella syndrome
title_fullStr Epidemiological analysis of rubella-confirmed cases from measles-suspected cases in Ethiopia: threat for congenital rubella syndrome
title_full_unstemmed Epidemiological analysis of rubella-confirmed cases from measles-suspected cases in Ethiopia: threat for congenital rubella syndrome
title_short Epidemiological analysis of rubella-confirmed cases from measles-suspected cases in Ethiopia: threat for congenital rubella syndrome
title_sort epidemiological analysis of rubella-confirmed cases from measles-suspected cases in ethiopia: threat for congenital rubella syndrome
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915192/
https://www.ncbi.nlm.nih.gov/pubmed/35225215
http://dx.doi.org/10.1017/S0950268822000279
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