Necroptosis-driving genes RIPK1, RIPK3 and MLKL-p are associated with intratumoral CD3(+) and CD8(+) T cell density and predict prognosis in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is a highly lethal cancer and the second leading cause of cancer-related deaths worldwide. As demonstrated in other solid neoplasms and HCC, infiltrating CD8(+) T cells seem to be related to a better prognosis, but the mechanisms affecting the immune landsc...

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Detalles Bibliográficos
Autores principales: Nicolè, Lorenzo, Sanavia, Tiziana, Cappellesso, Rocco, Maffeis, Valeria, Akiba, Jun, Kawahara, Akihiko, Naito, Yoshiki, Radu, Claudia Maria, Simioni, Paolo, Serafin, Davide, Cortese, Giuliana, Guido, Maria, Zanus, Giacomo, Yano, Hirohisa, Fassina, Ambrogio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915343/
https://www.ncbi.nlm.nih.gov/pubmed/35264437
http://dx.doi.org/10.1136/jitc-2021-004031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915343/
https://www.ncbi.nlm.nih.gov/pubmed/35264437
http://dx.doi.org/10.1136/jitc-2021-004031

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