Cargando…

What is the definition of acute episodic and chronic pain in critically ill neonates and infants? A global, four-stage consensus and validation study

OBJECTIVES: To define and validate types of pain in critically ill neonates and infants by researchers and clinicians working in the neonatal intensive care unit (NICU) and high dependency unit (HDU). DESIGN: A qualitative descriptive mixed-methods design. PROCEDURE/S: Each stage of the study was bu...

Descripción completa

Detalles Bibliográficos
Autores principales: Ilhan, Emre, Pacey, Verity, Brown, Laura, Spence, Kaye, van Ganzewinkel, Christ-jan, Pillai Riddell, Rebecca, Campbell-Yeo, Marsha, Stevens, Bonnie J, Eriksson, Mats, Shah, Vibhuti, Anand, Kanwaljeet J S, Bellieni, Carlo, Daly, Mandy, Johnston, Celeste, Hush, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915348/
https://www.ncbi.nlm.nih.gov/pubmed/35264356
http://dx.doi.org/10.1136/bmjopen-2021-055255
_version_ 1784668001139687424
author Ilhan, Emre
Pacey, Verity
Brown, Laura
Spence, Kaye
van Ganzewinkel, Christ-jan
Pillai Riddell, Rebecca
Campbell-Yeo, Marsha
Stevens, Bonnie J
Eriksson, Mats
Shah, Vibhuti
Anand, Kanwaljeet J S
Bellieni, Carlo
Daly, Mandy
Johnston, Celeste
Hush, Julia
author_facet Ilhan, Emre
Pacey, Verity
Brown, Laura
Spence, Kaye
van Ganzewinkel, Christ-jan
Pillai Riddell, Rebecca
Campbell-Yeo, Marsha
Stevens, Bonnie J
Eriksson, Mats
Shah, Vibhuti
Anand, Kanwaljeet J S
Bellieni, Carlo
Daly, Mandy
Johnston, Celeste
Hush, Julia
author_sort Ilhan, Emre
collection PubMed
description OBJECTIVES: To define and validate types of pain in critically ill neonates and infants by researchers and clinicians working in the neonatal intensive care unit (NICU) and high dependency unit (HDU). DESIGN: A qualitative descriptive mixed-methods design. PROCEDURE/S: Each stage of the study was built on and confirmed the previous stages. Stage 1 was an expert panel to develop definitions; stage 2 was a different expert panel made up of neonatal clinicians to propose clinical characteristics associated with the definitions from stage 1; stage 3 was a focus group of neonatal clinicians to provide clinical case scenarios associated with each definition and clinical characteristics; and stage 4 was a survey administered to neonatal clinicians internationally to test the validity of the definitions using the clinical case scenarios. RESULTS: In stage 1, the panel (n=10) developed consensus definitions for acute episodic pain and chronic pain in neonates and infants. In stage 2, a panel (n=8) established clinical characteristics that may be associated with each definition. In stage 3, a focus group (n=11) created clinical case scenarios of neonates and infants with acute episodic pain, chronic pain and no pain using the definitions and clinical characteristics. In stage 4, the survey (n=182) revealed that the definitions allowed an excellent level of discrimination between case scenarios that described neonates and infants with acute episodic pain and chronic pain (area under the receiver operating characteristic=0.87 and 0.89, respectively). CONCLUSIONS: This four-stage study enabled the development of consensus-based and clinically valid definitions of acute episodic pain and chronic pain. There is a need to define and validate other pain types to inform a taxonomy of pain experienced by neonates and infants in the NICU and HDU.
format Online
Article
Text
id pubmed-8915348
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BMJ Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-89153482022-03-25 What is the definition of acute episodic and chronic pain in critically ill neonates and infants? A global, four-stage consensus and validation study Ilhan, Emre Pacey, Verity Brown, Laura Spence, Kaye van Ganzewinkel, Christ-jan Pillai Riddell, Rebecca Campbell-Yeo, Marsha Stevens, Bonnie J Eriksson, Mats Shah, Vibhuti Anand, Kanwaljeet J S Bellieni, Carlo Daly, Mandy Johnston, Celeste Hush, Julia BMJ Open Paediatrics OBJECTIVES: To define and validate types of pain in critically ill neonates and infants by researchers and clinicians working in the neonatal intensive care unit (NICU) and high dependency unit (HDU). DESIGN: A qualitative descriptive mixed-methods design. PROCEDURE/S: Each stage of the study was built on and confirmed the previous stages. Stage 1 was an expert panel to develop definitions; stage 2 was a different expert panel made up of neonatal clinicians to propose clinical characteristics associated with the definitions from stage 1; stage 3 was a focus group of neonatal clinicians to provide clinical case scenarios associated with each definition and clinical characteristics; and stage 4 was a survey administered to neonatal clinicians internationally to test the validity of the definitions using the clinical case scenarios. RESULTS: In stage 1, the panel (n=10) developed consensus definitions for acute episodic pain and chronic pain in neonates and infants. In stage 2, a panel (n=8) established clinical characteristics that may be associated with each definition. In stage 3, a focus group (n=11) created clinical case scenarios of neonates and infants with acute episodic pain, chronic pain and no pain using the definitions and clinical characteristics. In stage 4, the survey (n=182) revealed that the definitions allowed an excellent level of discrimination between case scenarios that described neonates and infants with acute episodic pain and chronic pain (area under the receiver operating characteristic=0.87 and 0.89, respectively). CONCLUSIONS: This four-stage study enabled the development of consensus-based and clinically valid definitions of acute episodic pain and chronic pain. There is a need to define and validate other pain types to inform a taxonomy of pain experienced by neonates and infants in the NICU and HDU. BMJ Publishing Group 2022-03-08 /pmc/articles/PMC8915348/ /pubmed/35264356 http://dx.doi.org/10.1136/bmjopen-2021-055255 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Paediatrics
Ilhan, Emre
Pacey, Verity
Brown, Laura
Spence, Kaye
van Ganzewinkel, Christ-jan
Pillai Riddell, Rebecca
Campbell-Yeo, Marsha
Stevens, Bonnie J
Eriksson, Mats
Shah, Vibhuti
Anand, Kanwaljeet J S
Bellieni, Carlo
Daly, Mandy
Johnston, Celeste
Hush, Julia
What is the definition of acute episodic and chronic pain in critically ill neonates and infants? A global, four-stage consensus and validation study
title What is the definition of acute episodic and chronic pain in critically ill neonates and infants? A global, four-stage consensus and validation study
title_full What is the definition of acute episodic and chronic pain in critically ill neonates and infants? A global, four-stage consensus and validation study
title_fullStr What is the definition of acute episodic and chronic pain in critically ill neonates and infants? A global, four-stage consensus and validation study
title_full_unstemmed What is the definition of acute episodic and chronic pain in critically ill neonates and infants? A global, four-stage consensus and validation study
title_short What is the definition of acute episodic and chronic pain in critically ill neonates and infants? A global, four-stage consensus and validation study
title_sort what is the definition of acute episodic and chronic pain in critically ill neonates and infants? a global, four-stage consensus and validation study
topic Paediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915348/
https://www.ncbi.nlm.nih.gov/pubmed/35264356
http://dx.doi.org/10.1136/bmjopen-2021-055255
work_keys_str_mv AT ilhanemre whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT paceyverity whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT brownlaura whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT spencekaye whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT vanganzewinkelchristjan whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT pillairiddellrebecca whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT campbellyeomarsha whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT stevensbonniej whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT erikssonmats whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT shahvibhuti whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT anandkanwaljeetjs whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT bellienicarlo whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT dalymandy whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT johnstonceleste whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy
AT hushjulia whatisthedefinitionofacuteepisodicandchronicpainincriticallyillneonatesandinfantsaglobalfourstageconsensusandvalidationstudy