Molecular epidemiology of the SARS-CoV-2 variant Omicron BA.2 sub-lineage in Denmark, 29 November 2021 to 2 January 2022

Following emergence of the SARS-CoV-2 variant Omicron in November 2021, the dominant BA.1 sub-lineage was replaced by the BA.2 sub-lineage in Denmark. We analysed the first 2,623 BA.2 cases from 29 November 2021 to 2 January 2022. No epidemiological or clinical differences were found between individ...

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Detalles Bibliográficos
Autores principales: Fonager, Jannik, Bennedbæk, Marc, Bager, Peter, Wohlfahrt, Jan, Ellegaard, Kirsten Maren, Ingham, Anna Cäcilia, Edslev, Sofie Marie, Stegger, Marc, Sieber, Raphael Niklaus, Lassauniere, Ria, Fomsgaard, Anders, Lillebaek, Troels, Svarrer, Christina Wiid, Møller, Frederik Trier, Møller, Camilla Holten, Legarth, Rebecca, Sydenham, Thomas Vognbjerg, Steinke, Kat, Paulsen, Sarah Juel, Castruita, José Alfredo Samaniego, Schneider, Uffe Vest, Schouw, Christian Højte, Nielsen, Xiaohui Chen, Overvad, Maria, Nielsen, Rikke Thoft, Marvig, Rasmus L, Pedersen, Martin Schou, Nielsen, Lene, Nilsson, Line Lynge, Bybjerg-Grauholm, Jonas, Tarpgaard, Irene Harder, Ebsen, Tine Snejbjerg, Lam, Janni Uyen Hoa, Gunalan, Vithiagaran, Rasmussen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915403/
https://www.ncbi.nlm.nih.gov/pubmed/35272746
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.10.2200181
Descripción
Sumario:Following emergence of the SARS-CoV-2 variant Omicron in November 2021, the dominant BA.1 sub-lineage was replaced by the BA.2 sub-lineage in Denmark. We analysed the first 2,623 BA.2 cases from 29 November 2021 to 2 January 2022. No epidemiological or clinical differences were found between individuals infected with BA.1 versus BA.2. Phylogenetic analyses showed a geographic east-to-west transmission of BA.2 from the Capital Region with clusters expanding after the Christmas holidays. Mutational analysis shows distinct differences between BA.1 and BA.2.

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