Cargando…

Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal down-regulated neuroimmune and synaptic pathways

Recent genetic studies have identified variants associated with bipolar disorder (BD), but it remains unclear how brain gene expression is altered in BD, and how genetic risk for BD may contribute to these alterations. Here, we obtained transcriptomes from subgenual anterior cingulate cortex and amy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zandi, Peter P., Jaffe, Andrew E., Goes, Fernando S., Burke, Emily E., Collado-Torres, Leonardo, Huuki-Myers, Louise, Seyedian, Arta, Lin, Yian, Seifuddin, Fayaz, Pirooznia, Mehdi, Ross, Christopher A., Kleinman, Joel E., Weinberger, Daniel R., Hyde, Thomas M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915427/ https://www.ncbi.nlm.nih.gov/pubmed/35260864 http://dx.doi.org/10.1038/s41593-022-01024-6

Ejemplares similares

Systematic review of genome-wide gene expression studies of bipolar disorder
por: Seifuddin, Fayaz, et al.
Publicado: (2013)

SVAw - a web-based application tool for automated surrogate variable analysis of gene expression studies
por: Pirooznia, Mehdi, et al.
Publicado: (2013)

Converging Evidence for Epistasis between ANK3 and Potassium Channel Gene KCNQ2 in Bipolar Disorder
por: Judy, Jennifer Toolan, et al.
Publicado: (2013)

Genome-wide association of mood-incongruent psychotic bipolar disorder
por: Goes, F S, et al.
Publicado: (2012)

Interplay of Amygdala and Cingulate Plasticity in Emotional Fear
por: Toyoda, Hiroki, et al.
Publicado: (2011)

An amygdala-to-cingulate cortex circuit for conflicting choices in chronic pain
por: Valentinova, Kristina, et al.
Publicado: (2023)

Genetic and environmental contributions to ancestry differences in gene expression in the human brain
por: Benjamin, Kynon J.M., et al.
Publicado: (2023)

Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection
por: Singh, Komudi, et al.
Publicado: (2020)

Amygdala and cingulate structure is associated with stereotype on sex-role
por: Takeuchi, Hikaru, et al.
Publicado: (2015)

Whole-genome CNV analysis: advances in computational approaches
por: Pirooznia, Mehdi, et al.
Publicado: (2015)

Translating Fear Circuitry: Amygdala Projections to Subgenual and Perigenual Anterior Cingulate in the Macaque
por: Sharma, K K, et al.
Publicado: (2020)

Integrated single cell and unsupervised spatial transcriptomic analysis defines molecular anatomy of the human dorsolateral prefrontal cortex
por: Huuki-Myers, Louise, et al.
Publicado: (2023)

lncRNAKB, a knowledgebase of tissue-specific functional annotation and trait association of long noncoding RNA
por: Seifuddin, Fayaz, et al.
Publicado: (2020)

Contributions of anterior cingulate cortex and basolateral amygdala to decision confidence and learning under uncertainty
por: Stolyarova, A., et al.
Publicado: (2019)

IKAP—Identifying K mAjor cell Population groups in single-cell RNA-sequencing analysis
por: Chen, Yun-Ching, et al.
Publicado: (2019)

The Role of the Subgenual Anterior Cingulate Cortex and Amygdala in Environmental Sensitivity to Infant Crying
por: Mutschler, Isabella, et al.
Publicado: (2016)

Income is associated with hippocampal/amygdala and education with cingulate cortex grey matter volume
por: Lotze, M., et al.
Publicado: (2020)

Emotion, motivation, decision-making, the orbitofrontal cortex, anterior cingulate cortex, and the amygdala
por: Rolls, Edmund T.
Publicado: (2023)

Divergent neuronal DNA methylation patterns across human cortical development reveal critical periods and a unique role of CpH methylation
por: Price, Amanda J., et al.
Publicado: (2019)

Smaller left anterior cingulate cortex in non-bipolar relatives of patients with bipolar disorder
por: Sanches, Marsal, et al.
Publicado: (2018)

Integrative network analysis identifies differential regulation of neuroimmune system in Schizophrenia and Bipolar disorder
por: Sahu, Ankur, et al.
Publicado: (2019)

Misregulation of ELK1, AP1, and E12 Transcription Factor Networks Is Associated with Melanoma Progression
por: Singh, Komudi, et al.
Publicado: (2020)

Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection
por: Singh, Komudi, et al.
Publicado: (2021)

Mapping DNA methylation across development, genotype, and schizophrenia in the human frontal cortex
por: Jaffe, Andrew E., et al.
Publicado: (2015)

Preserved emotional awareness of pain in a patient with extensive bilateral damage to the insula, anterior cingulate, and amygdala
por: Feinstein, Justin S., et al.
Publicado: (2015)

The neuroimmune axis of Alzheimer’s disease
por: Jorfi, Mehdi, et al.
Publicado: (2023)

Characterizing the nuclear and cytoplasmic transcriptomes in developing and mature human cortex uncovers new insight into psychiatric disease gene regulation
por: Price, Amanda J., et al.
Publicado: (2020)

Fear avoidance beliefs in back pain-free subjects are reflected by amygdala-cingulate responses
por: Meier, Michael L., et al.
Publicado: (2015)

Anterior cingulate cortex and its input to the basolateral amygdala control innate fear response
por: Jhang, Jinho, et al.
Publicado: (2018)

Preliminary Evidence That CD38 Moderates the Association of Neuroticism on Amygdala-Subgenual Cingulate Connectivity
por: Tabak, Benjamin A., et al.
Publicado: (2020)

Developmental regulation of human cortex transcription and its clinical relevance at base resolution
por: Jaffe, Andrew E., et al.
Publicado: (2014)

Altered expression of histamine signaling genes in autism spectrum disorder
por: Wright, C, et al.
Publicado: (2017)

Psychopathic traits influence amygdala–anterior cingulate cortex connectivity during facial emotion processing
por: Ewbank, Michael P, et al.
Publicado: (2018)

Pre- and perinatal hypoxia associated with hippocampus/amygdala volume in bipolar disorder
por: Haukvik, U. K., et al.
Publicado: (2014)

Predicting cognitive behavioral therapy response in social anxiety disorder with anterior cingulate cortex and amygdala during emotion regulation
por: Klumpp, Heide, et al.
Publicado: (2017)

In Vivo Amygdala Nuclei Volumes in Schizophrenia and Bipolar Disorders
por: Barth, Claudia, et al.
Publicado: (2021)

Neuroimmune perspectives in sepsis
por: Ulloa, Luis, et al.
Publicado: (2009)

Neuroimmune Communication in the Kidney
por: Nakamura, Yasuna, et al.
Publicado: (2020)

Neuroimmune Pathophysiology in Asthma
por: Pavón-Romero, Gandhi F., et al.
Publicado: (2021)

Erratum to: Practical impacts of genomic data “cleaning” on biological discovery using surrogate variable analysis
por: Jaffe, Andrew E., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_d9ibtt1ap1f31hnft6c2ik4qvg