HDAC7 promotes NSCLC proliferation and metastasis via stabilization by deubiquitinase USP10 and activation of β-catenin-FGF18 pathway

BACKGROUND: Histone deacetylases (HDACs) play crucial roles in cancers, but the role and mechanism of HDAC7 in NSCLC have not been fully understood. METHODS: A total of 319 patients with non-small cell lung cancer (NSCLC) who underwent surgery were enrolled in this study. Immunohistochemistry and Ka...

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Detalles Bibliográficos
Autores principales: Guo, Kai, Ma, Zhiqiang, Zhang, Yujiao, Han, Lu, Shao, Changjian, Feng, Yingtong, Gao, Fei, Di, Shouyin, Zhang, Zhipei, Zhang, Jiao, Tabbò, Fabrizio, Ekman, Simon, Suda, Kenichi, Cappuzzo, Federico, Han, Jing, Li, Xiaofei, Yan, Xiaolong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915541/
https://www.ncbi.nlm.nih.gov/pubmed/35277183
http://dx.doi.org/10.1186/s13046-022-02266-9

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