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Analgesic Effects of Oxycodone in Combination With Risperidone or Ziprasidone: Results From a Pilot Randomized Controlled Trial in Healthy Volunteers

BACKGROUND AND OBJECTIVES: Patients taking opioids are at risk of developing dependence and possibly abuse. Given the role of the mesolimbic dopamine system in opioid reward, blocking dopamine D2 receptors should limit the abuse liability of opioid analgesics. This pilot study evaluates the analgesi...

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Detalles Bibliográficos
Autores principales: Nagpal, Ameet S., Lodge, Daniel J., Potter, Jennifer S., Frazer, Alan, Tragus, Robin, Curtis, Megan E., Boley, Angela M., Eckmann, Maxim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915578/
https://www.ncbi.nlm.nih.gov/pubmed/35295795
http://dx.doi.org/10.3389/fpain.2022.752256