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Analgesic Effects of Oxycodone in Combination With Risperidone or Ziprasidone: Results From a Pilot Randomized Controlled Trial in Healthy Volunteers
BACKGROUND AND OBJECTIVES: Patients taking opioids are at risk of developing dependence and possibly abuse. Given the role of the mesolimbic dopamine system in opioid reward, blocking dopamine D2 receptors should limit the abuse liability of opioid analgesics. This pilot study evaluates the analgesi...
Autores principales: | Nagpal, Ameet S., Lodge, Daniel J., Potter, Jennifer S., Frazer, Alan, Tragus, Robin, Curtis, Megan E., Boley, Angela M., Eckmann, Maxim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915578/ https://www.ncbi.nlm.nih.gov/pubmed/35295795 http://dx.doi.org/10.3389/fpain.2022.752256 |
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