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Estimation of the octanol-water distribution coefficient of basic compounds by a cationic microemulsion electrokinetic chromatography system
The octanol-water partition coefficient (P(o/w)), or the octanol-water distribution coefficient (D(o/w)) for ionized compounds, is a key parameter in the drug development process. In a previous work, this parameter was estimated through the retention factor measurements in a sodium dodecyl sulfate (...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Association of Physical Chemists
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915598/ https://www.ncbi.nlm.nih.gov/pubmed/35299774 http://dx.doi.org/10.5599/admet.760 |