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Evaluation of Inhalation Exposures and Potential Health Impacts of Ingredient Mixtures Using in vitro to in vivo Extrapolation

In vitro methods offer opportunities to provide mechanistic insight into bioactivity as well as human-relevant toxicological assessments compared to animal testing. One of the challenges for this task is putting in vitro bioactivity data in an in vivo exposure context, for which in vitro to in vivo...

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Detalles Bibliográficos
Autores principales: Zhang, Jingjie, Chang, Xiaoqing, Holland, Tessa L., Hines, David E., Karmaus, Agnes L., Bell, Shannon, Lee, K. Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915826/
https://www.ncbi.nlm.nih.gov/pubmed/35295123
http://dx.doi.org/10.3389/ftox.2021.787756