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Evaluation of Inhalation Exposures and Potential Health Impacts of Ingredient Mixtures Using in vitro to in vivo Extrapolation
In vitro methods offer opportunities to provide mechanistic insight into bioactivity as well as human-relevant toxicological assessments compared to animal testing. One of the challenges for this task is putting in vitro bioactivity data in an in vivo exposure context, for which in vitro to in vivo...
Autores principales: | Zhang, Jingjie, Chang, Xiaoqing, Holland, Tessa L., Hines, David E., Karmaus, Agnes L., Bell, Shannon, Lee, K. Monica |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915826/ https://www.ncbi.nlm.nih.gov/pubmed/35295123 http://dx.doi.org/10.3389/ftox.2021.787756 |
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