Cargando…

Canadian Regulatory Perspective on Next Generation Risk Assessments for Pest Control Products and Industrial Chemicals

In 2012, the Council of Canadian Academies published the expert panel on integrated testing of pesticide’s report titled: Integrating emerging technologies into chemical safety assessment. This report was prepared for the Government of Canada in response to a request from the Minister of Health and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bhuller, Yadvinder, Ramsingh, Deborah, Beal, Marc, Kulkarni, Sunil, Gagne, Matthew, Barton-Maclaren, Tara S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915837/ https://www.ncbi.nlm.nih.gov/pubmed/35295100 http://dx.doi.org/10.3389/ftox.2021.748406

Ejemplares similares

Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of industrial chemicals and pesticides for effects on human health
por: Stucki, Andreas O., et al.
Publicado: (2022)

Novel machine learning models to predict endocrine disruption activity for high-throughput chemical screening
por: Collins, Sean P., et al.
Publicado: (2022)

In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals
por: Matteo, Geronimo, et al.
Publicado: (2022)

Candidate Proficiency Test Chemicals to Address Industrial Chemical Applicability Domains for in vitro Human Cytochrome P450 Enzyme Induction
por: Jacobs, Miriam Naomi, et al.
Publicado: (2022)

Prioritization of chemicals in food for risk assessment by integrating exposure estimates and new approach methodologies: A next generation risk assessment case study
por: Luijten, Mirjam, et al.
Publicado: (2022)

Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment
por: Farmahin, Reza, et al.
Publicado: (2016)

Next Generation Reproductive and Developmental Toxicology: Crosstalk Into the Future
por: Hougaard, Karin Sørig
Publicado: (2021)

Mentoring and Supporting Our Next Generation of Women Toxicologists
por: Swanson, Hollie I.
Publicado: (2022)

Development of a New Threshold of Toxicological Concern Database of Non-cancer Toxicity Endpoints for Industrial Chemicals
por: Yamada, Takashi, et al.
Publicado: (2021)

Mining toxicogenomic data for dose-responsive pathways: implications in advancing next-generation risk assessment
por: Barutcu, A. Rasim, et al.
Publicado: (2023)

From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow
por: Reardon, Anthony J. F., et al.
Publicado: (2023)

Next Generation Risk Assessment of the Anti-Androgen Flutamide Including the Contribution of Its Active Metabolite Hydroxyflutamide
por: van Tongeren, Tessa C.A., et al.
Publicado: (2022)

Next-generation effects of fetal and lactational exposure to the neonicotinoid pesticide clothianidin on the immune system and gut microbiota
por: MURATA, Midori, et al.
Publicado: (2023)

Editorial: In vitro toxicogenomics (TGx) in hazard and risk assessment
por: Beal, Marc A., et al.
Publicado: (2023)

Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Predict the Cardiotoxicity Potential of Next Generation Nicotine Products
por: Simms, Liam, et al.
Publicado: (2022)

Article title: Transcriptional profiling efficacy to define biological activity similarity for cosmetic ingredients’ safety assessment based on next-generation read-across
por: Naciff, Jorge M., et al.
Publicado: (2022)

Editorial: Women in regulatory toxicology: 2021
por: Ågerstrand, Marlene, et al.
Publicado: (2022)

Advancing chemical safety assessment through an omics-based characterization of the test system-chemical interaction
por: del Giudice, Giusy, et al.
Publicado: (2023)

Chemical Pneumonitis from Hydrocarbon Aspiration
por: Pham, Keimanh, et al.
Publicado: (2008)

Editorial: Chemical allergy and the relevance of new models
por: Pallardy, Marc, et al.
Publicado: (2023)

Chemical toxic exposures and chronic ocular pain
por: Graca, Mateusz, et al.
Publicado: (2023)

Ophthalmic manifestations and management considerations for emerging chemical threats
por: Menke, Bryant A., et al.
Publicado: (2023)

Regulatory Testing for Endocrine Disruptors; Need for Validated Methods and Integrated Approaches
por: Grignard, Elise, et al.
Publicado: (2022)

Editorial: Chemical testing using new approach methodologies (NAMs)
por: Stucki, Andreas O., et al.
Publicado: (2022)

The development and function of the brain barriers – an overlooked consideration for chemical toxicity
por: Bell, Kiersten S., et al.
Publicado: (2022)

Brazil’s Regulatory Context for Using New Approach Methodologies (NAMs) on the Registration of Products
por: Villela, Izabel Vianna, et al.
Publicado: (2022)

Comparison of Short-Term Estrogenicity Tests for Identification of Hormone-Disrupting Chemicals
por: Andersen, Helle Raun, et al.
Publicado: (1999)

Contact chemical burn of the hand caused by xylene: A case report
por: Dewar, Zachary Ewan, et al.
Publicado: (2020)

Data curation to support toxicity assessments using the Integrated Chemical Environment
por: Daniel, Amber B., et al.
Publicado: (2022)

B-1 cells in immunotoxicology: Mechanisms underlying their response to chemicals and particles
por: Hiéronimus, Léa, et al.
Publicado: (2023)

Sex blind: bridging the gap between drug exposure and sex-related gene expression in Danio rerio using next-generation sequencing (NGS) data and a literature review to find the missing links in pharmaceutical and environmental toxicology studies
por: King, Alex C., et al.
Publicado: (2023)

Characterization of Chemical Suicides in the United States and Its Adverse Impact on Responders and Bystanders
por: Anderson, Ayana R.
Publicado: (2016)

High-throughput AR dimerization assay identifies androgen disrupting chemicals and metabolites
por: Brown, Evan C., et al.
Publicado: (2023)

Integration of Adverse Outcome Pathways, Causal Networks and ‘Omics to Support Chemical Hazard Assessment
por: Perkins, Edward J., et al.
Publicado: (2022)

Developmental Exposure to Endocrine Disrupting Chemicals and Its Impact on Cardio-Metabolic-Renal Health
por: Singh, Radha Dutt, et al.
Publicado: (2021)

The Evolving E-cigarette: Comparative Chemical Analyses of E-cigarette Vapor and Cigarette Smoke
por: Cunningham, Anthony, et al.
Publicado: (2020)

Use of new approach methodologies (NAMs) to meet regulatory requirements for the assessment of tobacco and other nicotine-containing products
por: Miller-Holt, Jacqueline, et al.
Publicado: (2022)

How to facilitate the implementation of 3D models in China by applying good in vitro method practice for regulatory use
por: Liu, Yanfeng, et al.
Publicado: (2023)

Derivation of New Threshold of Toxicological Concern Values for Exposure via Inhalation for Environmentally-Relevant Chemicals
por: Nelms, Mark D., et al.
Publicado: (2020)

Mapping Mechanistic Pathways of Acute Oral Systemic Toxicity Using Chemical Structure and Bioactivity Measurements
por: Edwards, Stephen W., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_lk64kkehmvkndbsthmhtcaje8e