Cargando…

Adverse Outcome Pathway Development for Assessment of Lung Carcinogenicity by Nanoparticles

Lung cancer, one of the most common and deadly forms of cancer, is in some cases associated with exposure to certain types of particles. With the rise of nanotechnology, there is concern that some engineered nanoparticles may be among such particles. In the absence of epidemiological evidence, asses...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nymark, Penny, Karlsson, Hanna L., Halappanavar, Sabina, Vogel, Ulla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915843/ https://www.ncbi.nlm.nih.gov/pubmed/35295099 http://dx.doi.org/10.3389/ftox.2021.653386

Ejemplares similares

Development of a data-driven approach to Adverse Outcome Pathway network generation: a case study on the EATS-modalities
por: Wiklund, Linus, et al.
Publicado: (2023)

SciRAPnano: a pragmatic and harmonized approach for quality evaluation of in vitro toxicity data to support risk assessment of nanomaterials
por: Shao, Gen, et al.
Publicado: (2023)

In silico approaches in carcinogenicity hazard assessment: case study of pregabalin, a nongenotoxic mouse carcinogen
por: Keller, Douglas A., et al.
Publicado: (2023)

Primary and Secondary Genotoxicity of Nanoparticles: Establishing a Co-Culture Protocol for Assessing Micronucleus Using Flow Cytometry
por: Vallabani, N. V. Srikanth, et al.
Publicado: (2022)

Integration of Adverse Outcome Pathways, Causal Networks and ‘Omics to Support Chemical Hazard Assessment
por: Perkins, Edward J., et al.
Publicado: (2022)

Mapping Adverse Outcome Pathways for Kidney Injury as a Basis for the Development of Mechanism-Based Animal-Sparing Approaches to Assessment of Nephrotoxicity
por: Mally, Angela, et al.
Publicado: (2022)

Reactive Oxygen Species in the Adverse Outcome Pathway Framework: Toward Creation of Harmonized Consensus Key Events
por: Tanabe, Shihori, et al.
Publicado: (2022)

Evidenced-Based Approaches to Support the Development of Endocrine-Mediated Adverse Outcome Pathways: Challenges and Opportunities
por: Audouze, Karine, et al.
Publicado: (2021)

An Adverse Outcome Pathway for Decreased Lung Function Focusing on Mechanisms of Impaired Mucociliary Clearance Following Inhalation Exposure
por: Luettich, Karsta, et al.
Publicado: (2021)

Expanding adverse outcome pathways towards one health models for nanosafety
por: Saarimäki, Laura Aliisa, et al.
Publicado: (2023)

New approach methodologies to facilitate and improve the hazard assessment of non-genotoxic carcinogens—a PARC project
por: Audebert, Marc, et al.
Publicado: (2023)

Caenorhabditis elegans Neurotoxicity Testing: Novel Applications in the Adverse Outcome Pathway Framework
por: Sammi, Shreesh Raj, et al.
Publicado: (2022)

Threshold of Toxicological Concern—An Update for Non-Genotoxic Carcinogens
por: Batke, Monika, et al.
Publicado: (2021)

From Causal Networks to Adverse Outcome Pathways: A Developmental Neurotoxicity Case Study
por: Ramšak, Živa, et al.
Publicado: (2022)

Application of the Adverse Outcome Pathway Concept to In Vitro Nephrotoxicity Assessment: Kidney Injury due to Receptor-Mediated Endocytosis and Lysosomal Overload as a Case Study
por: Jarzina, Sebastian, et al.
Publicado: (2022)

Cow’s milk neutralizes the cytotoxicity of acrolein, a putative carcinogen in cigarette smoke
por: MIZUTA, Ryushin, et al.
Publicado: (2018)

Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale
por: Halappanavar, Sabina, et al.
Publicado: (2020)

Daphnia as a model organism to probe biological responses to nanomaterials—from individual to population effects via adverse outcome pathways
por: Reilly, Katie, et al.
Publicado: (2023)

Gene expression profiling after exposure to a chemical carcinogen, Pentabrominated Diphenyl Ether, at different life stages
por: Shockley, Keith R., et al.
Publicado: (2023)

Physiologically Relevant Estrogen Receptor Alpha Pathway Reporters for Single-Cell Imaging-Based Carcinogenic Hazard Assessment of Estrogenic Compounds
por: Duijndam, Britt, et al.
Publicado: (2021)

Integration of data across toxicity endpoints for improved safety assessment of chemicals: the example of carcinogenicity assessment
por: Madia, Federica, et al.
Publicado: (2021)

A Case Study on Integrating a New Key Event Into an Existing Adverse Outcome Pathway on Oxidative DNA Damage: Challenges and Approaches in a Data-Rich Area
por: Huliganga, Elizabeth, et al.
Publicado: (2022)

Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes
por: Labib, Sarah, et al.
Publicado: (2016)

A framework for the use of single-chemical transcriptomics data in predicting the hazards associated with complex mixtures of polycyclic aromatic hydrocarbons
por: Labib, Sarah, et al.
Publicado: (2016)

A new approach to the classification of carcinogenicity
por: Doe, John E., et al.
Publicado: (2022)

Particle Safety Assessment in Additive Manufacturing: From Exposure Risks to Advanced Toxicology Testing
por: Alijagic, Andi, et al.
Publicado: (2022)

Development and Application of Nanoparticle-Nanopolymer Composite Spheres for the Study of Environmental Processes
por: Rauschendorfer, Robert J., et al.
Publicado: (2021)

Impact of acute intoxication on quantitative pupillometry assessment in the emergency department
por: Jolkovsky, Eliana L., et al.
Publicado: (2022)

Mapping DEHP to the adverse outcome pathway network for human female reproductive toxicity
por: Pogrmic-Majkic, Kristina, et al.
Publicado: (2022)

INVESTIGATING ALTERNATIVES TO THE FISH EARLY-LIFE STAGE TEST: A STRATEGY FOR DISCOVERING AND ANNOTATING ADVERSE OUTCOME PATHWAYS FOR EARLY FISH DEVELOPMENT
por: Villeneuve, Daniel, et al.
Publicado: (2014)

Exposure Assessment of Silver and Gold Nanoparticles Generated During the Synthesis Process in a South African Research Laboratory
por: Masekameni, Masilu D., et al.
Publicado: (2022)

Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework
por: Nikota, Jake, et al.
Publicado: (2017)

Mining toxicogenomic data for dose-responsive pathways: implications in advancing next-generation risk assessment
por: Barutcu, A. Rasim, et al.
Publicado: (2023)

Characterization of Chemical Suicides in the United States and Its Adverse Impact on Responders and Bystanders
por: Anderson, Ayana R.
Publicado: (2016)

Reports of Doses Administered and Adverse Reactions to Snake Antivenom Used in Uruguay in 2018
por: Negrin, Alba, et al.
Publicado: (2021)

Adverse effects of maternal exposure to bisphenol F on the anxiety- and depression-like behavior of offspring
por: OHTANI, Naoko, et al.
Publicado: (2016)

Advancing food safety risk assessment in China: development of new approach methodologies (NAMs)
por: Yang, Daoyuan, et al.
Publicado: (2023)

Do macrophages play a role in the adverse effects of endocrine disrupting chemicals (EDCs) on testicular functions?
por: Cui, Haoyi, et al.
Publicado: (2023)

Aryl Hydrocarbon Receptor Signaling Synergizes with TLR/NF-κB-Signaling for Induction of IL-22 Through Canonical and Non-Canonical AhR Pathways
por: Ishihara, Yasuhiro, et al.
Publicado: (2022)

Transgenerational effects of developmental neurotoxicity induced by exposure to a no-observed-adverse-effect level (NOAEL) of neonicotinoid pesticide clothianidin
por: SHODA, Asuka, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_444sf8t4fmij4m6c3m5k51r62k