Discriminating Spontaneous From Cigarette Smoke and THS 2.2 Aerosol Exposure-Related Proliferative Lung Lesions in A/J Mice by Using Gene Expression and Mutation Spectrum Data

Mice, especially A/J mice, have been widely employed to elucidate the underlying mechanisms of lung tumor formation and progression and to derive human-relevant modes of action. Cigarette smoke (CS) exposure induces tumors in the lungs; but, non-exposed A/J mice will also develop lung tumors spontan...

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Detalles Bibliográficos
Autores principales: Xiang, Yang, Luettich, Karsta, Martin, Florian, Battey, James N. D., Trivedi, Keyur, Neau, Laurent, Wong, Ee Tsin, Guedj, Emmanuel, Dulize, Remi, Peric, Dariusz, Bornand, David, Ouadi, Sonia, Sierro, Nicolas, Büttner, Ansgar, Ivanov, Nikolai V., Vanscheeuwijck, Patrick, Hoeng, Julia, Peitsch, Manuel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915865/
https://www.ncbi.nlm.nih.gov/pubmed/35295134
http://dx.doi.org/10.3389/ftox.2021.634035

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