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Dissecting Drug-Induced Cytotoxicity and Metabolic Dysfunction in Conditionally Immortalized Human Proximal Tubule Cells

Fourteen to 26 percent of all hospitalized cases of acute kidney injury are explained by drug-induced toxicity, emphasizing the importance of proper strategies to pre-clinically assess renal toxicity. The MTT assay is widely used as a measure of cell viability, but largely depends on cellular metabo...

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Detalles Bibliográficos
Autores principales:	Hoogstraten, Charlotte A., Smeitink, Jan A. M., Russel, Frans G. M., Schirris, Tom J. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915871/ https://www.ncbi.nlm.nih.gov/pubmed/35295229 http://dx.doi.org/10.3389/ftox.2022.842396

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