Cargando…
6-Formylindolo[3,2-b]carbazole, a Potent Ligand for the Aryl Hydrocarbon Receptor Produced Both Endogenously and by Microorganisms, can Either Promote or Restrain Inflammatory Responses
The aryl hydrocarbon receptor (AHR) binds major physiological modifiers of the immune system. The endogenous 6-formylindolo[3,2-b]carbazole (FICZ), which binds with higher affinity than any other compound yet tested, including TCDD, plays a well-documented role in maintaining the homeostasis of the...
Autor principal: | Rannug, Agneta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915874/ https://www.ncbi.nlm.nih.gov/pubmed/35295226 http://dx.doi.org/10.3389/ftox.2022.775010 |
Ejemplares similares
-
Activation of aryl hydrocarbon receptor by 6‐formylindolo[3,2‐b]carbazole alleviated acute kidney injury by repressing inflammation and apoptosis
por: Tao, Sibei, et al.
Publicado: (2020) -
Editorial: Role of the Aryl Hydrocarbon Receptor in Immune Modulation
por: Kaplan, Barbara L. F., et al.
Publicado: (2022) -
The Aryl Hydrocarbon Receptor Suppresses Chronic Smoke-Induced Pulmonary Inflammation
por: Guerrina, Necola, et al.
Publicado: (2021) -
The tryptophan-derived endogenous arylhydrocarbon receptor ligand 6-formylindolo[3,2-b]carbazole (FICZ) is a nanomolar UVA-photosensitizer in epidermal keratinocytes
por: Park, Sophia L., et al.
Publicado: (2014) -
Methylated phenanthrenes are more potent than phenanthrene in a bioassay of human aryl hydrocarbon receptor (AhR) signaling
por: Sun, Yue, et al.
Publicado: (2014)