ΔNp63-Senataxin circuit controls keratinocyte differentiation by promoting the transcriptional termination of epidermal genes

ΔNp63, a master regulator of epithelial biology, is involved in regulating epithelial stem cell function, maintaining the integrity of stratified epithelial cells, and committing epidermal cells to the differentiation program. To this end, ΔNp63 exploits several direct mechanisms. Here, we elucidate...

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Detalles Bibliográficos
Autores principales: Gatti, Veronica, Fierro, Claudia, Compagnone, Mirco, La Banca, Veronica, Mauriello, Alessandro, Montanaro, Manuela, Scalera, Stefano, De Nicola, Francesca, Candi, Eleonora, Ricci, Francesco, Fania, Luca, Melino, Gerry, Peschiaroli, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915885/
https://www.ncbi.nlm.nih.gov/pubmed/35235452
http://dx.doi.org/10.1073/pnas.2104718119

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