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Molecular mechanism underlying the TLR4 antagonistic and antiseptic activities of papiliocin, an insect innate immune response molecule

Antimicrobial peptides are innate immune molecules playing essential roles in insects, which lack the adaptive immune system. Insects possess Toll9, the innate pattern-recognition receptor highly similar to the mammalian Toll-like receptor 4 (TLR4), which is involved in recognizing lipopolysaccharid...

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Detalles Bibliográficos
Autores principales: Krishnan, Manigandan, Choi, Joonhyeok, Jang, Ahjin, Choi, Sungjae, Yeon, Jiwon, Jang, Mihee, Lee, Yeongjoon, Son, Kkabi, Shin, Soon Young, Jeong, Myeong Seon, Kim, Yangmee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915966/
https://www.ncbi.nlm.nih.gov/pubmed/35238667
http://dx.doi.org/10.1073/pnas.2115669119