Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury

BACKGROUND: Inflammation is a significant contributor to neuronal death and dysfunction following traumatic brain injury (TBI). Recent evidence suggests that interferons may be a key regulator of this response. Our studies evaluated the role of the Cyclic GMP-AMP Synthase-Stimulator of Interferon Ge...

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Detalles Bibliográficos
Autores principales: Fritsch, Lauren E., Ju, Jing, Gudenschwager Basso, Erwin Kristobal, Soliman, Eman, Paul, Swagatika, Chen, Jiang, Kaloss, Alexandra M., Kowalski, Elizabeth A., Tuhy, Taylor C., Somaiya, Rachana Deven, Wang, Xia, Allen, Irving Coy, Theus, Michelle H., Pickrell, Alicia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916033/
https://www.ncbi.nlm.nih.gov/pubmed/35283725
http://dx.doi.org/10.3389/fnmol.2022.852243

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