Impact of Donepezil on Brain Glucose Metabolism Assessed Using [(18)F]2-Fluoro-2-deoxy-D-Glucose Positron Emission Tomography Imaging in a Mouse Model of Alzheimer’s Disease Induced by Intracerebroventricular Injection of Amyloid-Beta Peptide

Translational methods are needed to monitor the impact of the Alzheimer’s disease (AD) and therapies on brain function in animal models and patients. The formation of amyloid plaques was investigated using [(18)F]florbetapir autoradiography in a mouse model of AD consisting in unilateral intracerebr...

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Detalles Bibliográficos
Autores principales: Hugon, Gaëlle, Goutal, Sébastien, Sarazin, Marie, Bottlaender, Michel, Caillé, Fabien, Droguerre, Marine, Charvériat, Mathieu, Winkeler, Alexandra, Tournier, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916213/
https://www.ncbi.nlm.nih.gov/pubmed/35281502
http://dx.doi.org/10.3389/fnins.2022.835577

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