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Endoglin Wild Type and Variants Associated With Hereditary Hemorrhagic Telangiectasia Type 1 Undergo Distinct Cellular Degradation Pathways

Endoglin, also known as cluster of differentiation 105 (CD105), is an auxiliary receptor in the TGFβ signaling pathway. It is predominantly expressed in endothelial cells as a component of the heterotetrameric receptor dimers comprising type I, type II receptors and the binding ligands. Mutations in...

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Detalles Bibliográficos
Autores principales:	Gariballa, Nesrin, Kizhakkedath, Praseetha, Akawi, Nadia, John, Anne, Ali, Bassam R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916587/ https://www.ncbi.nlm.nih.gov/pubmed/35281255 http://dx.doi.org/10.3389/fmolb.2022.828199

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