Cargando…

Profound gene expression changes in the epithelial monolayer of active ulcerative colitis and Crohn’s disease

In recent years it has become apparent that the epithelium is highly involved in inflammatory bowel disease (IBD) pathophysiology. The majority of gene expression studies of IBD are generated from heterogeneous biopsies, providing no distinction between immune cells, the epithelium and other mucosal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sæterstad, Siri, Østvik, Ann Elisabet, Røyset, Elin Synnøve, Bakke, Ingunn, Sandvik, Arne Kristian, Granlund, Atle van Beelen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916644/ https://www.ncbi.nlm.nih.gov/pubmed/35275975 http://dx.doi.org/10.1371/journal.pone.0265189

Ejemplares similares

Expression of neutrophil gelatinase-associated lipocalin (NGAL) in the gut in Crohn’s disease
por: Thorsvik, Silje, et al.
Publicado: (2018)

Mucosal and faecal neutrophil gelatinase-associated lipocalin as potential biomarkers for collagenous colitis
por: Bakke, Ingunn, et al.
Publicado: (2021)

Intestinal Epithelial Cells Express Immunomodulatory ISG15 During Active Ulcerative Colitis and Crohn’s Disease
por: Østvik, Ann Elisabet, et al.
Publicado: (2020)

Bacterial Mucosa-associated Microbiome in Inflamed and Proximal Noninflamed Ileum of Patients With Crohn’s Disease
por: Olaisen, Maya, et al.
Publicado: (2020)

Ulcer‐associated cell lineage expresses genes involved in regeneration and is hallmarked by high neutrophil gelatinase‐associated lipocalin (NGAL) levels
por: Thorsvik, Silje, et al.
Publicado: (2019)

Mucosal 5‐aminosalicylic acid concentration, drug formulation and mucosal microbiome in patients with quiescent ulcerative colitis
por: Olaisen, Maya, et al.
Publicado: (2019)

Deep learning‐based image analysis reveals significant differences in the number and distribution of mucosal CD3 and γδ T cells between Crohn's disease and ulcerative colitis
por: Røyset, Elin Synnøve, et al.
Publicado: (2022)

Expression of CCL20 and Its Corresponding Receptor CCR6 Is Enhanced in Active Inflammatory Bowel Disease, and TLR3 Mediates CCL20 Expression in Colonic Epithelial Cells
por: Skovdahl, Helene Kolstad, et al.
Publicado: (2015)

Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease
por: Escudero-Hernández, Celia, et al.
Publicado: (2021)

C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release
por: Skovdahl, Helene Kolstad, et al.
Publicado: (2018)

Tofacitinib Downregulates TNF and Poly(I:C)-Dependent MHC-II Expression in the Colonic Epithelium
por: Gopalakrishnan, Shreya, et al.
Publicado: (2022)

The ileal fungal microbiota is altered in Crohn's disease and is associated with the disease course
por: Olaisen, Maya, et al.
Publicado: (2022)

Host–Viral Interactions in the Pathogenesis of Ulcerative Colitis
por: Bruland, Torunn, et al.
Publicado: (2021)

Whole Genome Gene Expression Meta-Analysis of Inflammatory Bowel Disease Colon Mucosa Demonstrates Lack of Major Differences between Crohn's Disease and Ulcerative Colitis
por: Granlund, Atle van Beelen, et al.
Publicado: (2013)

REG gene expression in inflamed and healthy colon mucosa explored by in situ hybridisation
por: van Beelen Granlund, Atle, et al.
Publicado: (2013)

Activation of REG family proteins in colitis
por: Granlund, Atle Vand Beelen, et al.
Publicado: (2011)

The Water Channel Aquaporin 8 is a Critical Regulator of Intestinal Fluid Homeostasis in Collagenous Colitis
por: Escudero-Hernández, Celia, et al.
Publicado: (2020)

Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids
por: Gopalakrishnan, Shreya, et al.
Publicado: (2023)

Physiological hypoxia improves growth and functional differentiation of human intestinal epithelial organoids
por: Walaas, Gunnar Andreas, et al.
Publicado: (2023)

Subtle Protective Roles of Clusterin in Gastric Metaplasia After Acute Oxyntic Atrophy
por: Vange, Pål, et al.
Publicado: (2018)

Patient Derived Colonoids as Drug Testing Platforms–Critical Importance of Oxygen Concentration
por: Skovdahl, Helene Kolstad, et al.
Publicado: (2021)

Relevance of TNBS-Colitis in Rats: A Methodological Study with Endoscopic, Histologic and Transcriptomic Characterization and Correlation to IBD
por: Brenna, Øystein, et al.
Publicado: (2013)

Correction: Relevance of TNBS-Colitis in Rats: A Methodological Study with Endoscopic, Histologic and Transcriptomic Characterization and Correlation to IBD
por: Brenna, Øystein, et al.
Publicado: (2013)

Code-Free Development and Deployment of Deep Segmentation Models for Digital Pathology
por: Pettersen, Henrik Sahlin, et al.
Publicado: (2022)

Crohn's disease and ulcerative colitis Surgical management
por: Wilkinson, A J
Publicado: (1996)

Mucosal Barrier in Ulcerative Colitis and Crohn's Disease
por: Dorofeyev, A. E., et al.
Publicado: (2013)

The safety of vedolizumab for ulcerative colitis and Crohn's disease
por: Colombel, Jean-Frédéric, et al.
Publicado: (2017)

Ulcerative Colitis and Crohn's Disease: Similarities and Distinctions
por: Sawyerr, Af M, et al.
Publicado: (1994)

Review of pregnancy in Crohn’s disease and ulcerative colitis
por: Laube, Robyn, et al.
Publicado: (2021)

Profound loss of neprilysin accompanied by decreased levels of neuropeptides and increased CRP in ulcerative colitis
por: Sargın, Zeynep Gök, et al.
Publicado: (2017)

Expressing the Differences between Crohn Disease and Ulcerative Colitis
por: Wijmenga, Cisca
Publicado: (2005)

Carbohydrate Intake in the Etiology of Crohn's Disease and Ulcerative Colitis
por: Chan, Simon S. M., et al.
Publicado: (2014)

The Changing Prognosis of Ulcerative Colitis and Crohn Disease by Decades
por: Korelitz, Burton I, et al.
Publicado: (2021)

Diagnosis of Crohn’s disease and ulcerative colitis using the microbiome
por: Kang, Da-Yeon, et al.
Publicado: (2023)

Plasma microRNA Profile Differentiates Crohn’s Colitis From Ulcerative Colitis
por: Netz, Uri, et al.
Publicado: (2018)

The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease
por: Brenna, Øystein, et al.
Publicado: (2015)

Is there a role for vedolizumab in the treatment of ulcerative colitis and Crohn’s disease?
por: Gilroy, Leah, et al.
Publicado: (2014)

Gastritis Associated with Initially Pediatric Crohn's Disease and Ulcerative Colitis
por: Basturk, Ahmet, et al.
Publicado: (2018)

Crohn’s Disease and Ulcerative Colitis Show Unique Cytokine Profiles
por: Nemeth, Zoltan H, et al.
Publicado: (2017)

Tofacitinib, two-faced Janus in ulcerative colitis and Crohn’s disease?
por: Biemans, Vince BC, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fnom5646ram0vq3c5lkv2b95ib