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GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate

GATA4/5/6 transcription factors play essential, conserved roles in heart development. To understand how GATA4/5/6 modulates the mesoderm-to-cardiac fate transition, we labeled, isolated, and performed single-cell gene expression analysis on cells that express gata5 at precardiac time points spanning...

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Detalles Bibliográficos
Autores principales: Song, Mengyi, Yuan, Xuefei, Racioppi, Claudia, Leslie, Meaghan, Stutt, Nathan, Aleksandrova, Anastasiia, Christiaen, Lionel, Wilson, Michael D., Scott, Ian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916722/
https://www.ncbi.nlm.nih.gov/pubmed/35275720
http://dx.doi.org/10.1126/sciadv.abg0834

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