Structural basis for HCMV Pentamer recognition by neuropilin 2 and neutralizing antibodies

Human cytomegalovirus (HCMV) encodes multiple surface glycoprotein complexes to infect a variety of cell types. The HCMV Pentamer, composed of gH, gL, UL128, UL130, and UL131A, enhances entry into epithelial, endothelial, and myeloid cells by interacting with the cell surface receptor neuropilin 2 (...

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Detalles Bibliográficos
Autores principales: Wrapp, Daniel, Ye, Xiaohua, Ku, Zhiqiang, Su, Hang, Jones, Harrison G., Wang, Nianshuang, Mishra, Akaash K., Freed, Daniel C., Li, Fengsheng, Tang, Aimin, Li, Leike, Jaijyan, Dabbu Kumar, Zhu, Hua, Wang, Dai, Fu, Tong-Ming, Zhang, Ningyan, An, Zhiqiang, McLellan, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916728/
https://www.ncbi.nlm.nih.gov/pubmed/35275718
http://dx.doi.org/10.1126/sciadv.abm2546

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