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Progressive axonopathy when oligodendrocytes lack the myelin protein CMTM5

Oligodendrocytes facilitate rapid impulse propagation along the axons they myelinate and support their long-term integrity. However, the functional relevance of many myelin proteins has remained unknown. Here, we find that expression of the tetraspan-transmembrane protein CMTM5 (chemokine-like facto...

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Detalles Bibliográficos
Autores principales: Buscham, Tobias J, Eichel-Vogel, Maria A, Steyer, Anna M, Jahn, Olaf, Strenzke, Nicola, Dardawal, Rakshit, Memhave, Tor R, Siems, Sophie B, Müller, Christina, Meschkat, Martin, Sun, Ting, Ruhwedel, Torben, Möbius, Wiebke, Krämer-Albers, Eva-Maria, Boretius, Susann, Nave, Klaus-Armin, Werner, Hauke B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916772/
https://www.ncbi.nlm.nih.gov/pubmed/35274615
http://dx.doi.org/10.7554/eLife.75523