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Apelin signaling dependent endocardial protrusions promote cardiac trabeculation in zebrafish

During cardiac development, endocardial cells (EdCs) produce growth factors to promote myocardial morphogenesis and growth. In particular, EdCs produce neuregulin which is required for ventricular cardiomyocytes (CMs) to seed the multicellular ridges known as trabeculae. Defects in neuregulin signal...

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Detalles Bibliográficos
Autores principales:	Qi, Jialing, Rittershaus, Annegret, Priya, Rashmi, Mansingh, Shivani, Stainier, Didier YR, Helker, Christian SM
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916774/ https://www.ncbi.nlm.nih.gov/pubmed/35225788 http://dx.doi.org/10.7554/eLife.73231

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