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Tunneling Nanotube-Mediated Mitochondrial Transfer Rescues Nucleus Pulposus Cells from Mitochondrial Dysfunction and Apoptosis

Stem cell-based therapy has been indicated to be beneficial for intervertebral disc regeneration. However, the underlying mechanisms have not been fully identified. The present study showed that bone marrow mesenchymal stem cells (BMSCs) donated mitochondria to adjacent nucleus pulposus cells (NPCs)...

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Detalles Bibliográficos
Autores principales: Yang, Fan, Zhang, Yanbin, Liu, Sheng, Xiao, Jiheng, He, Yuxin, Shao, Zengwu, Zhang, Yuhui, Cai, Xianyi, Xiong, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916857/
https://www.ncbi.nlm.nih.gov/pubmed/35281461
http://dx.doi.org/10.1155/2022/3613319