A Case of Anti-SAE1 Dermatomyositis

INTRODUCTION: Anti-SAE1 antibodies have a low prevalence in dermatomyositis patients. Case Description. A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron's papules, and erythematous rash. She had an interstitial lung disease (ILD) with a si...

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Detalles Bibliográficos
Autores principales: de Vries, Max, Schreurs, Marco W. J., Ahsmann, Els J. M., Spee-Dropkova, Marcela, Karim, Faiz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8916888/
https://www.ncbi.nlm.nih.gov/pubmed/35280599
http://dx.doi.org/10.1155/2022/9000608
Descripción
Sumario:INTRODUCTION: Anti-SAE1 antibodies have a low prevalence in dermatomyositis patients. Case Description. A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron's papules, and erythematous rash. She had an interstitial lung disease (ILD) with a significant decrease in lung function. There was no muscle involvement. Immunological laboratory test results showed strongly positive anti-SAE1 antibodies. Glucocorticoid treatment resulted in remission of dermatomyositis. CONCLUSION: Anti-SAE antibodies in dermatomyositis patients are closely linked to unique clinical features.

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