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Platelets differentially modulate CD4(+) Treg activation via GPIIa/IIIb-, fibrinogen-, and PAR4-dependent pathways
CD4(+)FoxP3(+) regulatory T cells (CD4(+) Tregs) are known to dampen inflammation following severe trauma. Platelets were shown to augment their posttraumatic activation in burn injury, but the exact mechanisms remain unclear. We hypothesized that platelet activation mechanisms via GPIIb/IIIa, fibri...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917040/ https://www.ncbi.nlm.nih.gov/pubmed/34932195 http://dx.doi.org/10.1007/s12026-021-09258-5 |