Cargando…

High prevalence of intrathecal IgA synthesis in multiple sclerosis patients

The detection of intrathecal IgA synthesis (IAS) in multiple sclerosis (MS) could be underestimated. To assess it, we develop a highly sensitive assay based on isoelectric focusing (IEF). 151 MS patients and 53 controls with different neurological diseases were recruited. IgA concentration was analy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Muñoz, Úrsula, Sebal, Cristina, Escudero, Esther, García Sánchez, Maria Isabel, Urcelay, Elena, Jayo, Asier, Arroyo, Rafael, García-Martínez, Maria A., Álvarez-Lafuente, Roberto, Sádaba, María C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917141/ https://www.ncbi.nlm.nih.gov/pubmed/35277553 http://dx.doi.org/10.1038/s41598-022-08099-y

Ejemplares similares

Serum levels of IgM to phosphatidylcholine predict the response of multiple sclerosis patients to natalizumab or IFN-β
por: Muñoz, Úrsula, et al.
Publicado: (2022)

IgM to phosphatidylcholine in multiple sclerosis patients: from the diagnosis to the treatment
por: Sánchez-Vera, Isabel, et al.
Publicado: (2023)

DRB1*03:01 Haplotypes: Differential Contribution to Multiple Sclerosis Risk and Specific Association with the Presence of Intrathecal IgM Bands
por: de la Concha, Emilio G., et al.
Publicado: (2012)

Anti-Human Herpesvirus 6A/B IgG Correlates with Relapses and Progression in Multiple Sclerosis
por: Ortega-Madueño, Isabel, et al.
Publicado: (2014)

Serum antibodies to phosphatidylcholine in MS
por: Sádaba, Maria Cruz, et al.
Publicado: (2020)

Multiple sclerosis retrovirus-like envelope gene: Role of the chromosome 20 insertion
por: Varadé, Jezabel, et al.
Publicado: (2015)

Microbiota, IgA and Multiple Sclerosis
por: Boussamet, Léo, et al.
Publicado: (2022)

MicroRNAs of Human Herpesvirus 6A and 6B in Serum and Cerebrospinal Fluid of Multiple Sclerosis Patients
por: Domínguez-Mozo, María I., et al.
Publicado: (2020)

Mitochondrial Impairments in Peripheral Blood Mononuclear Cells of Multiple Sclerosis Patients
por: Domínguez-Mozo, María Inmaculada, et al.
Publicado: (2022)

HERV-W polymorphism in chromosome X is associated with multiple sclerosis risk and with differential expression of MSRV
por: García-Montojo, Marta, et al.
Publicado: (2014)

Epstein-Barr Virus and multiple sclerosis in a Spanish cohort: A two-years longitudinal study
por: Domínguez-Mozo, María Inmaculada, et al.
Publicado: (2022)

Epstein-Barr Virus Load Correlates with Multiple Sclerosis-Associated Retrovirus Envelope Expression
por: Pérez-Pérez, Silvia, et al.
Publicado: (2022)

Human Endogenous Retrovirus HERV-Fc1 Association with Multiple Sclerosis Susceptibility: A Meta-Analysis
por: de la Hera, Belén, et al.
Publicado: (2014)

IgA vasculitis in children
por: Penido, Maria Goretti Moreira Guimarães, et al.
Publicado: (2022)

Recombinant IgA Antibodies
por: Yoo, Esther M., et al.
Publicado: (2007)

Epidemiology of multiple sclerosis and vitamin D levels in Lanzarote, Canary Islands, Spain
por: Pérez-Pérez, Silvia, et al.
Publicado: (2019)

The Role of IgA in the Pathogenesis of IgA Nephropathy
por: Perše, Martina, et al.
Publicado: (2019)

K Index is a Reliable Marker of Intrathecal Synthesis, and an Alternative to IgG Index in Multiple Sclerosis Diagnostic Work-Up
por: Crespi, Ilaria, et al.
Publicado: (2019)

Non-classical forms of pemphigus: pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus
por: Porro, Adriana Maria, et al.
Publicado: (2014)

Predicting Aggressive Multiple Sclerosis With Intrathecal IgM Synthesis Among Patients With a Clinically Isolated Syndrome
por: Monreal, Enric, et al.
Publicado: (2021)

IgA nephropathy in IgG kappa multiple myeloma
por: Couto, Maria Eduarda, et al.
Publicado: (2021)

A Polymorphism Within the MBP Gene Is Associated With a Higher Relapse Number in Male Patients of Multiple Sclerosis
por: Espino-Paisán, Laura, et al.
Publicado: (2020)

A functional PTPN22 polymorphism associated with several autoimmune diseases is not associated with IgA deficiency in the Spanish population
por: Núñez, Concepción, et al.
Publicado: (2006)

IgA nephropathy following COVID-19 vaccination: challenges and perspectives
por: Niel, Olivier, et al.
Publicado: (2022)

IgA Vasculitis and IgA Nephropathy: Same Disease?
por: Pillebout, Evangeline
Publicado: (2021)

MHC2TA mRNA levels and human herpesvirus 6 in multiple sclerosis patients treated with interferon beta along two-year follow-up
por: Dominguez-Mozo, Maria Inmaculada, et al.
Publicado: (2012)

Validation of the International IgA Nephropathy Prediction Tool in the Greek Registry of IgA Nephropathy
por: Papasotiriou, Marios, et al.
Publicado: (2022)

Relationship between Gd-IgA1 and TNFR1 in IgA nephropathy and IgA vasculitis nephritis in children – multicenter study
por: Mizerska-Wasiak, Małgorzata, et al.
Publicado: (2021)

Racial heterogeneity of IgA1 hinge-region O-glycoforms in patients with IgA nephropathy
por: Ohyama, Yukako, et al.
Publicado: (2022)

Tripterygium Wilfordii inhibits tonsillar IgA production by downregulating IgA class switching in IgA nephropathy
por: Li, Huining, et al.
Publicado: (2017)

IgA Staining Patterns Differentiate Between IgA Nephropathy and IgA-Dominant Infection-Associated Glomerulonephritis
por: Brodsky, Sergey V., et al.
Publicado: (2020)

Temporal invariance and clonal uniformity of brain and cerebrospinal IgG, IgA, and IgM in multiple sclerosis
Publicado: (1986)

Increased Urinary IgA in Paediatric IgA Vasculitis Nephritis
por: Marro, Julien, et al.
Publicado: (2022)

Current understanding of IgA antibodies in the pathogenesis of IgA nephropathy
por: Nihei, Yoshihito, et al.
Publicado: (2023)

The Reibergram for immunoglobulin A in dogs: Evaluation of intrathecal IgA synthesis using a quotient graph in dogs with neurological diseases
por: Püschel, Mirja L., et al.
Publicado: (2022)

Predictive factors and early biomarkers of response in multiple sclerosis patients treated with natalizumab
por: Dominguez-Mozo, Maria Inmaculada, et al.
Publicado: (2020)

Secretory IgA as Biomarker for Gastrointestinal Nematodes Natural Infection in Different Breed Sheep
por: Castilla Gómez de Agüero, Verónica, et al.
Publicado: (2023)

Minimal-moderate variation of human oral virome and microbiome in IgA deficiency
por: de la Cruz Peña, Maria José, et al.
Publicado: (2021)

The Functional Role of IgA in the IgM/IgA-Enriched Immunoglobulin Preparation Trimodulin
por: Bohländer, Fabian, et al.
Publicado: (2021)

Herpesvirus Antibodies, Vitamin D and Short-Chain Fatty Acids: Their Correlation with Cell Subsets in Multiple Sclerosis Patients and Healthy Controls
por: Dominguez-Mozo, Maria Inmaculada, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5hnmesvhmee289vg2mlpqubhti