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Dysfunction of lipid storage droplet-2 suppresses endoreplication and induces JNK pathway-mediated apoptotic cell death in Drosophila salivary glands

The lipid storage droplet-2 (LSD-2) protein of Drosophila is a homolog of mammalian perilipin 2, which is essential for promoting lipid accumulation and lipid droplet formation. The function of LSD-2 as a regulator of lipolysis has also been demonstrated. However, other LSD-2 functions remain unclea...

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Detalles Bibliográficos
Autores principales: Binh, Tran Duy, Nguyen, Yen D. H., Pham, Tuan L. A., Komori, Kenichi, Nguyen, Thanh Q. C., Taninaka, Masahide, Kamei, Kaeko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917166/
https://www.ncbi.nlm.nih.gov/pubmed/35277579
http://dx.doi.org/10.1038/s41598-022-08299-6