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Follistatin-like 1 promotes proliferation of matured human hypoxic iPSC-cardiomyocytes and is secreted by cardiac fibroblasts

The human heart has limited regenerative capacity. Therefore, patients often progress to heart failure after ischemic injury, despite advances in reperfusion therapies generally decreasing mortality. Depending on its glycosylation state, Follistatin-like 1 (FSTL1) has been shown to increase cardiomy...

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Detalles Bibliográficos
Autores principales: Peters, Marijn C., Di Martino, Sofia, Boelens, Thomas, Qin, Jiabin, van Mil, Alain, Doevendans, Pieter A., Chamuleau, Steven A.J., Sluijter, Joost P.G., Neef, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8917270/
https://www.ncbi.nlm.nih.gov/pubmed/35317048
http://dx.doi.org/10.1016/j.omtm.2022.02.005